Evidence mapPaperPMID 39817208Full record

ArticleWorld journal of diabetes2025

Diabetes-inducing effects of bronchial asthma.

Mohammed Al-Beltagi, Adel Salah Bediwy, Nermin Kamal Saeed, Hosameldin A Bediwy, Reem Elbeltagi

Abstract read
In one paragraph

Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammed Al-BeltagiDepartment of Pediatric, Faculty of Medicine, Tanta University, Tanta 31511‎, Alghrabia, Egypt.
Adel Salah BediwyDepartment of Pulmonology, Faculty of Medicine, Tanta University, Tanta ‎‎31527, Alghrabia, Egypt.
Nermin Kamal SaeedMedical Microbiology Section, Department of Pathology, Salmaniya Medical Complex, ‎Ministry of Health, Kingdom of Bahrain, Manama 26671, Manama, Bahrain.
Hosameldin A BediwyFaculty of Medicine, Tanta University, Tanta 31527, Algharbia, Egypt.
Reem ElbeltagiDepartment of Medicine, The Royal College of Surgeons in Ireland-Bahrain, ‎Busiateen 15503, Muharraq, Bahrain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between diabetes mellitus (DM) and asthma is complex and can impact disease trajectories.

aimTo explore the bidirectional influences between the two conditions on clinical outcomes and disease control.

methodsWe systematically reviewed the literature on the relationship between DM and asthma, focusing on their impacts, mechanisms, and therapeutic implications. Various studies were assessed, which investigated the effect of glycemic control on asthma outcomes, lung function, and exacerbations. The study highlighted the role of specific diabetes medications in managing asthma.

resultsThe results showed that poor glycemic control in diabetes can exacerbate asthma, increase hospitalizations, and reduce lung function. Conversely, severe asthma, especially in obese individuals, can complicate diabetes management and make glycemic control more difficult. The diabetes-associated mechanisms, such as inflammation, microangiopathy, and oxidative stress, can exacerbate asthma and decrease lung function. Some diabetes medications exhibit anti-inflammatory effects that show promise in mitigating asthma exacerbations.

conclusionThe complex interrelationship between diabetes and asthma suggests bidirectional influences that affect disease course and outcomes. Inflammation and microvascular complications associated with diabetes may worsen asthma outcomes, while asthma severity, especially in obese individuals, complicates diabetes control. However, the current research has limitations, and more diverse longitudinal studies are required to establish causal relationships and identify effective treatment strategies for individuals with both conditions.

Indexed as

Asthma exacerbationBronchial asthmaDiabetes mellitusDisease interactionGlycemic controlLung functionMicroangiopathy

Identifiers

PMID39817208
PMCPMC11718464

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.