Evidence map›Paper›PMID 39817417›Full record

ArticleChembiochem : a European journal of chemical biology2025

Probing Native CB

Francesca Ciaramellano, Alessandro Leuti, Alexandrine D E Kurtz, Roman Sarott, Matthias Westphal, Patrick Pfaff, Uwe Grether, Erick M Carreira, Mauro Maccarrone, Sergio Oddi

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Probing Native CBChembiochem : a European journal of chemical biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesca CiaramellanoEuropean Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143, Rome, Italy.
Alessandro LeutiEuropean Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143, Rome, Italy.
Alexandrine D E KurtzDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100, Teramo, Italy.
Roman SarottLaboratorium für Organische Chemie, ETH Zurich, Vladimir-Prelog-Weg 3, Zurich, CH-8093, Switzerland.
Matthias WestphalLaboratorium für Organische Chemie, ETH Zurich, Vladimir-Prelog-Weg 3, Zurich, CH-8093, Switzerland.
Patrick PfaffLaboratorium für Organische Chemie, ETH Zurich, Vladimir-Prelog-Weg 3, Zurich, CH-8093, Switzerland.
Uwe GretherPharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel, CH-4070, Switzerland.
Erick M CarreiraLaboratorium für Organische Chemie, ETH Zurich, Vladimir-Prelog-Weg 3, Zurich, CH-8093, Switzerland.
Mauro MaccarroneEuropean Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143, Rome, Italy.
Sergio OddiEuropean Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143, Rome, Italy.ORCID https://orcid.org/0000-0002-6217-698X

Funding

Ministero dell'Università e della Ricerca P20222272N_01Ministero dell'Università e della Ricerca P20222272N_02
6 · The paper itself

Abstract

In this study, we employed a novel fluorescent probe, RO7304924 - which selectively targets cannabinoid 2 receptor (CB

Indexed as

Cell MembraneFluorescence Recovery After PhotobleachingFluorescent DyesReceptor, Cannabinoid, CB2AnimalsCHO CellsCricetinaeCricetulusFluorescent DyesReceptor, Cannabinoid, CB2advanced fluorescent probescannabinoid 2 receptorFRAPGPCRsmembrane receptor mobility

Identifiers

PMID39817417
PMCPMC12007070

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.