Evidence map›Paper›PMID 39822249›Full record

ArticleCureus2025

Neuromodulatory Treatment for Dizziness and Chronic Neurological Dysfunction in an Elderly Patient Using Radio Electric Asymmetric Conveyer (REAC) Neuro Psycho Physical Optimization (NPPO) Gamma Brain Wave Optimization (BWO-G): A Case Report.

Salvatore Rinaldi, Valeria Modestto', Arianna Rinaldi, Roseli Bittar, Jeanne Oiticica, Vania Fontani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salvatore RinaldiDepartment of Research, Department of Regenerative Medicine, Rinaldi Fontani Foundation, Florence, ITA.
Valeria Modestto'Department of Research, Rinaldi Fontani Foundation, Florence, ITA.
Arianna RinaldiDepartment of Research, Department of Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.
Roseli BittarDepartment of Otolaryngology, University of São Paulo School of Medicine, São Paulo, BRA.
Jeanne OiticicaDepartment of Otolaryngology, University of São Paulo School of Medicine, São Paulo, BRA.
Vania FontaniDepartment of Research, Department of Regenerative Medicine, Rinaldi Fontani Foundation, Florence, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 88-year-old woman presented with a longstanding history of dizziness, tremors, and progressive mental and physical decline, significantly impairing her mobility and autonomy. Recently discharged from an ICU, the patient required extensive support for daily activities. Diagnostic evaluations, including EEG and analysis, revealed irregular frequency peaks and altered cortical activity, particularly in the frontal and prefrontal regions. The patient underwent a cycle of 18 sessions of radio electric asymmetric conveyer (REAC) Neuro Psycho Physical Optimization (NPPO) gamma brain wave optimization (BWO-G), a neuromodulatory treatment aimed at restoring neurophysiological balance. Post-treatment, the patient demonstrated marked clinical improvements, including enhanced gait stability, reduced tremors, and improved cognitive function. Electroencephalography (EEG) and standardized low-resolution brain electromagnetic tomography (sLORETA) analysis confirmed these clinical improvements, showing normalized frequency peaks and improved cortical activity patterns in Brodmann areas 6, 24, 31, 4, and 32. This case highlights the potential of REAC NPPO BWO-G in addressing chronic neurological dysfunction and improving the quality of life in elderly patients. Furthermore, the broader applicability of this treatment suggests potential benefits for managing similar conditions in aging populations, such as Parkinson's disease, age-related cognitive decline, and post-stroke rehabilitation, where bioelectrical dysregulation plays a central role.

Indexed as

chronic neurological dysfunctioncognitive and motor recoverydizzinesselderly patientsgamma brain wave optimization (bwo-g)neuro psycho physical optimization (nppo)noninvasive neuromodulationradio electric asymmetric conveyer (reac)

Identifiers

PMID39822249
PMCPMC11736058

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.