Evidence map›Paper›PMID 39822413›Full record

ReviewCureus2024

Nuclear Factor of Activated T Cells (NFAT) Proteins as Targeted Molecules in Diseases: A Narrative Review.

Mohadese Mozafari, Siti Nurnasihah Md Hashim, Khairul Bariah Ahmad Amin Noordin, Siti Aishah Zainal, Ahmad Azlina

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohadese MozafariBasic and Medical Sciences Unit, School of Dental Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, MYS.
Siti Nurnasihah Md HashimBasic and Medical Sciences Unit, School of Dental Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, MYS.
Khairul Bariah Ahmad Amin NoordinBasic and Medical Sciences Unit, School of Dental Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, MYS.
Siti Aishah ZainalBasic and Medical Sciences Unit, School of Dental Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, MYS.
Ahmad AzlinaBasic and Medical Sciences Unit, School of Dental Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nuclear factor of activated T cells (NFAT) is a key player in the NFAT pathway, regulating various cellular processes physiologically and pathologically. NFAT signaling is implicated in developing multiple diseases, such as cancer progression, that are associated with angiogenesis. Despite numerous studies on NFAT, there is still a dearth of information on the proteins and signaling pathway compared to other established pathways. With five NFAT proteins in the spotlight, this review aims to update the understanding of their roles and signaling by analyzing the most recent studies on the NFAT pathway. The recent insights into NFAT proteins and their association with diseases enhance our understanding of these proteins and open the possibility of developing therapeutic strategies for such diseases.

Indexed as

angiogenesiscancerendothelial cellnfat pathwaynfat proteinsstem cell

Identifiers

PMID39822413
PMCPMC11736229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.