Evidence map›Paper›PMID 39822551›Full record

ArticleAmerican journal of translational research2024

Clinical prediction model for progression from henoch-schönlein purpura to nephritis in pediatric patients.

Linmei Guo, Aimin Zhu, Weiping Li, Fanxia Zeng, Fei Wang

Abstract read
In one paragraph

Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linmei GuoDepartment of Pediatrics, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.
Aimin ZhuDepartment of Pediatrics, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.
Weiping LiDepartment of Pediatrics, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.
Fanxia ZengDepartment of Pediatrics, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.
Fei WangDepartment of Pediatrics, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify independent risk factors for Henoch-Schönlein purpura nephritis (HSPN) in pediatric patients.

methodsThis study enrolled 180 pediatric patients (90 with HSP, 90 with HSPN) hospitalized at the 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from December 2022 to October 2023, with a follow-up of at least six months. Clinical data were collected at the time of the first onset of HSP. Logistic regression analysis identified risk factors, which were subsequently evaluated using Receiver Operating Characteristic (ROC) curve analysis, a calibration plot, a nomogram, and decision curve analysis.

resultsA predictive model was constructed based on serum cystatin C, serum creatinine, immunoglobulin M, and estimated glomerular filtration rate (eGFR). ROC curve analysis showed high predictive accuracy, with an AUC of 0.9444, sensitivity of 0.82, and specificity of 0.98 at the optimal cutoff point. The calibration curve indicated strong agreement between predicted and actual outcomes. Decision curve analysis suggested that the model provides significant net benefits across different risk thresholds.

conclusionThis model effectively predicts the risk of HSPN, facilitating early intervention and improved patient outcomes.

Indexed as

clinical prediction modelcystatin CHenoch-schönlein purpurahenoch-schönlein purpura nephritisnomogrampediatric patientsROC curve

Identifiers

PMID39822551
PMCPMC11733386

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.