ArticleScientific reports2025
Body Mass Index mediates the relationship between estimated glucose disposal rate and gallstones.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
This study examined the relationship between gallstones and estimated glucose disposal rate (eGDR) in people in the United States and the possible mediating function of body mass index (BMI). Data came from the National Health and Nutrition Examination Survey (NHANES), conducted between 2017 and March 2020. Logistic regression, subgroup analysis, smoothed curve fitting, and causal mediation studies were among the statistical techniques used to examine the participant data. There were 595 subjects with a gallstone diagnosis out of 5,656 total. A significant negative association between eGDR and gallstones was observed by fully adjusted multivariate logistic regression analysis with an OR of 0.90 and a 95% confidence interval (CI) of (0.83, 0.98). The mediation analysis indicated that BMI accounted for 58.58% of the relationship between eGDR and the occurrence of gallstones. This study identified a substantial non-linear negative relationship between the occurrence of gallstones and eGDR levels, with BMI acting as a mediating factor. A fresh viewpoint on gallstone therapy and prevention is offered by these findings.
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