Evidence map›Paper›PMID 39825615›Full record

ReviewGut microbes2025

Amanda H Lee, Daphne Michelle Rodriguez Jimenez, Marlies Meisel

Abstract readReview
In one paragraph

Review in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Indole-3-carboxaldehyde fromGut microbes · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Evaluation ofMicroorganisms · 2026
    Article
  9. Metagenomic Insights into Gut Microbiota Alterations FollowingInternational journal of molecular sciences · 2026
    Article
  10. Gut-testis axis: how microbiota influence male reproductive health.Asian biomedicine : research, reviews and news · 2026
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amanda H LeeDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Daphne Michelle Rodriguez JimenezDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Marlies MeiselDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-5156-8067

Funding

Project 5: Microenvironment manipulation using anti-angiogenics to improve immunotherapy in melanomaP50CA254865 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, HONG · 2021 to 2025
$10.4M
Systemic immunoregulatory consequences of bacterial translocation during health and diseaseR01DK130897 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MEISEL, MARLIES · 2021 to 2025
$2.2M
NCI NIH HHS P50 CA254865NIDDK NIH HHS R01 DK130897
6 · The paper itself

Abstract

The gut microbiome plays a key role in human health, influencing various biological processes and disease outcomes. The historical roots of probiotics are traced back to Nobel Laureate Élie Metchnikoff, who linked the longevity of Bulgarian villagers to their consumption of sour milk fermented by Lactobacilli. His pioneering work led to the global recognition of probiotics as beneficial supplements, now a multibillion-dollar industry. Modern probiotics have been extensively studied for their immunomodulatory effects.

Indexed as

Gastrointestinal MicrobiomeLimosilactobacillus reuteriProbioticsAnimalsHumansNeoplasmsAutoimmunitycancerimmune systemLimosilactobacillus reuteriprobioticsystemic disease

Identifiers

PMID39825615
PMCPMC12716054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.