Evidence map›Paper›PMID 39827342›Full record

ArticleBiotechnology for biofuels and bioproducts2025

Optimizing Phaeodactylum tricornutum cultivation: integrated strategies for enhancing biomass, lipid, and fucoxanthin production.

Mostafa E Elshobary, Walaa A Abo-Shanab, Stephan S W Ende, Mohammed Alquraishi, Rania A El-Shenody

Abstract read
In one paragraph

Article in Biotechnology for biofuels and bioproducts, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. RSC advances · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Harnessing microalgae for bioproducts: innovations in synthetic biology.World journal of microbiology & biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Synergistic Anti-Obesity Effects ofInternational journal of molecular sciences · 2025
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mostafa E ElshobaryBotany and Microbiology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt. mostafa_elshobary@science.tanta.edu.eg.
Walaa A Abo-ShanabBotany and Microbiology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Stephan S W EndeAquaculture Research, Alfred Wegener Institute (AWI) - Helmholtz Centre for Polar and Marine Research, Am Handelshafen, 27570, Bremerhaven, Germany.
Mohammed AlquraishiDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 11433, Riyadh, Saudi Arabia.
Rania A El-ShenodyBotany and Microbiology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhaeodactylum tricornutum is a versatile marine microalga renowned for its high-value metabolite production, including omega-3 fatty acids and fucoxanthin, with emerging potential for integrated biorefinery approaches that encompass biofuel and bioproduct generation. Therefore, in this study we aimed to optimize the cultivation conditions for boosting biomass, lipid, and fucoxanthin production in P. tricornutum, focusing on the impacts of different nutrient ratios (nitrogen, phosphorus, silicate), glycerol supplementation, and light regimes.

resultsOptimized medium (- 50%N%, + 50% P, Zero-Si, 2 g glycerol) under low-intensity blue light (100 μmol m⁻

conclusionOur optimization approach reveals the significant potential of P. tricornutum as a versatile microbial platform for biomass, lipid, and fucoxanthin production. The tailored cultivation strategy successfully enhanced biomass and lipid accumulation, with notable improvements in biodiesel properties through strategic nutrient and light regime manipulation. These findings demonstrate the critical role of precise cultivation conditions in optimizing microalgal metabolic performance for biotechnological applications.

Indexed as

Biodiesel propertiesDiatomFatty acid profileFucoxanthinLipid optimizationMixotrophic cultivation

Identifiers

PMID39827342
PMCPMC11742496

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.