Evidence map›Paper›PMID 39828641›Full record

ReviewJournal of cellular and molecular medicine2025

Trajectory of Cardiogenic Dementia: A New Perspective.

Nawaf AlRawili, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Maha M Abdel-Fattah, Nasser A Al-Harchan, Mubarak Alruwaili, Marios Papadakis, Athanasios Alexiou, Gaber El-Saber Batiha

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
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  11. The Glymphatic System and Its Role in Neurovascular Diseases.Journal of neuroendovascular therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nawaf AlRawiliDepartment of Internal Medicine, College of Medicine, Northern Border University, Arar, Saudi Arabia.
Hayder M Al-KuraishyDepartment of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq.
Ali I Al-GareebDepartment of Clinical Pharmacology, Jabir ibn Hayyan Medical University, Kufa, Iraq.
Maha M Abdel-FattahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0002-9019-8932
Nasser A Al-HarchanDepartment of Clinical Pharmacology, College of Dentistry, Al-Rasheed University, Baghdad, Iraq.
Mubarak AlruwailiDepartment of Internal Medicine, College of Medicine, Jouf University, Saudi Arabia.
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, University of Witten- Herdecke, Wuppertal, Germany.ORCID 0000-0002-9020-874X
Athanasios AlexiouUniversity Centre for Research & Development, Chandigarh University, Mohali, India.
Gaber El-Saber BatihaDepartment of Research & Development, AFNP Med, Wien, Austria.

Funding

Open Access funding enabled and organized by Projekt DEAL. This work was supported by the University of Witten-Herdecke Germany.
6 · The paper itself

Abstract

The functions of the heart and brain are closely linked and essential to support human life by the heart-brain axis, which is a complex interconnection between the heart and brain. Also, cardiac function and cerebral blood flow regulate the brain's metabolism and function. Therefore, deterioration of cardiac function may affect cognitive function and may increase the risk of dementia. Cardiogenic dementia is defined as a cognitive deterioration due to heart diseases such as heart failure, myocardial infarction, and atrial fibrillation. The prevalence of cognitive impairment in patients with heart failure was 29%. In addition, coronary artery disease (CAD) is also associated with the development of cognitive impairment. CAD and reduction of myocardial contractility reduced cerebral blood flow and increased the risk of dementia in CAD patients. Furthermore, myocardial infarction and subsequent systemic haemodynamic instability promote the development and progression of cardiogenic dementia. These findings indicated that many cardiac diseases are implicated in the development and progression of cognitive impairment. Nevertheless, the underlying mechanism for the development of cardiogenic dementia was not fully elucidated. Consequently, this review aims to discuss the potential mechanisms involved in the pathogenesis of cardiogenic dementia.

Indexed as

DementiaAnimalsAtrial FibrillationBrainCognitive DysfunctionCoronary Artery DiseaseHeart FailureHumansMyocardial Infarctioncardiogenic dementiacognitive impairmentheart failuremyocardial infarction and atrial fibrillation

Identifiers

PMID39828641
PMCPMC11742966

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.