ArticleInternational medical case reports journal2025
The Oncogenic Human Papillomavirus Involvement as a Risk Factor of Measles, Mumps, and Rubella Vaccine Immunotherapy Failure in Anogenital Warts.
Article in International medical case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Rapidly Progressive Perianal Giant Condyloma in an Immunocompetent Adolescent: An Unusual Abuse-Associated Case.Clinical, cosmetic and investigational dermatology · 2026Article
- Complete Regression of Anogenital Warts Following Intralesional Measles-Mumps-Rubella (MMR) Vaccine: A Case of Two.Clinical, cosmetic and investigational dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anogenital warts (AGW) including multiple types of human papillomavirus (HPV) are prevalent. In this context, oncogenic HPV infection leads to anogenital cancers and the lesion is more persistent. Several research on AGW therapy with measles, mumps, and rubella (MMR) vaccine injections have been successful without adverse effects. However, the effects of MMR immunotherapy for AGW on multiple HPV infections have not been reported. This research is a case report of AGW in a 17-year-old male treated with MMR. The inclusion criteria specified young age, indicative of a strong immunological status. Meanwhile, the exclusion criteria comprised immunocompromised conditions, such as HIV confirmed to be negative. Dermatological examination showed that the pubic region and penile shaft presented 51 verrucous papules for 6 months, with histopathological results supporting the diagnosis of AGW. Polymerase chain reaction (PCR) examination reported the inclusion of HPV types 6, 11, and 16. The subcutaneous MMR vaccine was injected into the deltoid area every 2 weeks for three sessions. Meanwhile, the treatment response was assessed by counting the number and measuring the size of the lesion. After three sessions of MMR immunotherapy, there was no improvement in the size or quantity of lesions. Based on previous reports, a higher clearance rate for MMR immunotherapy was found in warts with a duration of < 6 months, while oncogenic HPV genotypes, particularly HPV type 16, take longer to clear than others. The efficacy of subcutaneous MMR injection for AGW treatment was unfavorable due to oncogenic HPV types. AGW treated with MMR immunotherapy should investigate oncogenic HPV genotype. However, further research needs to be carried out to justify this conclusion due to the limitations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.