Evidence mapPaperPMID 39830065Full record

ArticleFrontiers in nutrition2024

Association between composite dietary antioxidant index and Epstein-Barr virus infection in children aged 6-19 years in the United States: from the national health and nutrition examination survey 2007-2010.

Wei Cheng, Yunfei Wang, Nan Ding, Rutao Xie

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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei ChengSurgery Department of Traditional Chinese Medicine, Longhua Hospital Affiliated to ShanghaiUniversity of Traditional Chinese Medicine, Shanghai, China.
Yunfei WangSurgery Department of Traditional Chinese Medicine, Longhua Hospital Affiliated to ShanghaiUniversity of Traditional Chinese Medicine, Shanghai, China.
Nan DingSurgery Department of Traditional Chinese Medicine, Longhua Hospital Affiliated to ShanghaiUniversity of Traditional Chinese Medicine, Shanghai, China.
Rutao XieSurgery Department of Traditional Chinese Medicine, Longhua Hospital Affiliated to ShanghaiUniversity of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Epstein-Barr virus (EBV) is a globally prevalent herpes virus associated with multiple diseases. Oxidative stress is closely related to EBV infection, latency, reactivation, and transformation. Antioxidant diet protects against EBV infection. Composite Dietary Antioxidant Index (CDAI), serving as a key measure of antioxidant intake, is a summary score of six dietary antioxidants, including vitamins A, C, and E, carotenoid, selenium, and zinc. Despite this, the association between CDAI and EBV infection remains uncertain. Methods: The aim of the study was to evaluate the association between CDAI and EBV infection using cross-sectional data from 3,318 children aged 6-19 years who participated in the American National Health and Nutrition Examination Survey between 2007 and 2010. Data on EBV results, CDAI, and several other essential variables were analyzed. Results: Compared with that of individuals in Q3 (-1.627--0.2727) in the multivariate weighted logistic regression model with full adjustment for confounding variables, the adjusted odds ratio (OR) for CDAI and EBV infection in those in Q1 (-6.613 - -2.9157), Q2 (-2.9158--1.626), Q4 (-0.2728-1.7601), and Q5 (1.7602-21.419) was 1.41 (95% CI: 1.01-1.96, Conclusion: Our results indicated that the association between CDAI and EBV infection in U.S. adolescents follows a U-shaped curve, with an inflection point around -0.81.This suggests that an antioxidant-rich diet in some amount could help reduce the risk of EBV infection. Future prospective and experimental studies are needed to confirm causality and clarify the exact mechanism concerning antioxidant diets with EBV infection.

Indexed as

childrencomposite dietary antioxidant indexEpstein–Barr virus infectionNational Health and Nutrition Examination SurveyU-shaped

Identifiers

PMID39830065
PMCPMC11738948

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.