Evidence map›Paper›PMID 39830147›Full record

ArticleJBMR plus2025

Circulating lipocalin-2 across the adult lifespan.

Carlie Bauer, Cassandra Smith, Sara Vogrin, Andrew S Palmer, Mary Woessner, Shanie Landen, Macsue Jacques, Elizabeth Byrnes, Nir Eynon, Marc Sim and 2 more

Abstract read
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carlie BauerInstitute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.
Cassandra SmithNutrition & Health Innovation Research Institute, Edith Cowan University, Joondalup, WA 6027, Australia.ORCID https://orcid.org/0000-0002-2517-2824
Sara VogrinAustralian Institute for Musculoskeletal Science, Victoria University, University of Melbourne, St Albans, VIC 3021, Australia.
Andrew S PalmerInstitute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.
Mary WoessnerInstitute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.
Shanie LandenCentre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
Macsue JacquesInstitute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.
Elizabeth ByrnesPathWest, QEII Medical Centre, Perth, WA 6009, Australia.
Nir EynonAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3168, Australia.
Marc SimNutrition & Health Innovation Research Institute, Edith Cowan University, Joondalup, WA 6027, Australia.
Joshua R LewisNutrition & Health Innovation Research Institute, Edith Cowan University, Joondalup, WA 6027, Australia.ORCID https://orcid.org/0000-0003-1003-8443
Itamar LevingerInstitute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.ORCID https://orcid.org/0000-0001-9194-2033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipocalin-2 (LCN2), a hormone produced by adipocytes, osteoblasts, and renal tubular cells, is implicated in age-related diseases, including cardio-metabolic disease. To understand the role LCN2 may play in pathological states, we first need to elucidate the relationship between circulating LCN2 with indices of cardio-metabolic health during "normal" aging. This study examined the relationship between serum levels of LCN2, age, and cardio-metabolic measures across the adult lifespan in males and females. We conducted a pooled cohort analysis including 124 community-dwelling males (

Indexed as

agingbone interactorsclinical trialscytokinesendocrine

Identifiers

PMID39830147
PMCPMC11739805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.