Evidence map›Paper›PMID 39830404›Full record

ArticleNational science review2025

A tactfully designed photothermal agent collaborating with ascorbic acid for boosting maxillofacial wound healing.

Yuxin Qian, Yiting Gao, Dong Wang, Shixuan Zhang, Qiuxia Luo, Guogang Shan, Mengmeng Lu, Dingyuan Yan, Ben Zhong Tang, Ming Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in National science review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Advances in electrical stimulation for wound healing.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuxin QianDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University. State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases. Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.
Yiting GaoInstitute of Functional Material Chemistry and National & Local United Engineering Lab for Power Battery, Faculty of Chemistry, Northeast Normal University, Changchun 130024, China.
Dong WangCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
Shixuan ZhangDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University. State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases. Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.
Qiuxia LuoCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
Guogang ShanInstitute of Functional Material Chemistry and National & Local United Engineering Lab for Power Battery, Faculty of Chemistry, Northeast Normal University, Changchun 130024, China.
Mengmeng LuDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University. State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases. Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.
Dingyuan YanCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
Ben Zhong TangCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.ORCID https://orcid.org/0009-0002-1396-4186
Ming ZhangDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University. State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases. Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maxillofacial injuries that may cause severe functional and aesthetic damage require effective and immediate management due to continuous exposure to diverse microbial populations. Moreover, drug resistance, biofilm formation, and oxidative stress significantly impede timely bacterial removal and immune function, making the exploration of advanced materials for maxillofacial wound healing an appealing yet highly challenging task. Herein, a near-infrared photothermal sterilization agent was designed, encapsulated with liposomes and coated with ascorbic acid known for its antioxidant and immune-regulatory functions. The resulting nanoparticles, 4TPE-C6T-TD@AA, effectively neutralize reactive oxygen species generated by lipopolysaccharides, facilitate the conversion of pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages, and eliminate >90% of

Indexed as

anti-inflammationmaxillofacial wound healingphotothermal sterilization

Identifiers

PMID39830404
PMCPMC11737384

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.