ArticleJournal of research in pharmacy practice
Cardiovascular Complications Following Acute Methadone Poisoning in Patients with and Without a History of Long-term Methadone Use.
Article in Journal of research in pharmacy practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of ischemic postconditioning on inflammatory and oxidative markers in methadone-treated rats during myocardial ischemia-reperfusion injury : Cardioprotective effects of IPoC in methadone exposure.European journal of applied physiology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Given the prevalence of methadone poisoning, this study was conducted to compare the cardiovascular complications following acute methadone poisoning in patients with and without a history of long-term methadone use. Methods: In this retrospective study, information related to patients with acute methadone poisoning hospitalized at Al-Zahra and Khorshid hospitals in Isfahan-Iran was collected from hospital archives and analyzed. Patients were divided into two groups with and without a history of long-term methadone use. Findings: The mean of corrected QT interval (QTc), QRS, and heart rate showed no significant differences between the two groups at three-time points: baseline (upon admission), 12 h, and 24 h after admission ( Conclusion: The results indicate that among the cardiovascular findings when analyzing the electrocardiograms of patients with acute methadone poisoning, only QT dispersion differed between patients with and without a history of long-term methadone use. Cardiovascular events resulting from methadone poisoning are the significant factors contributing to patient mortality, highlighting the need for the careful management of methadone use in these patients.
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Registered trials
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