Evidence map›Paper›PMID 39831473›Full record

ArticleJournal of veterinary internal medicine

Characterization of post-ictal clinical signs in dogs with idiopathic epilepsy: A questionnaire-based study.

Aran Nagendran, Julie A Nettifee, Dani Carter, Karen R Muñana

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Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Aran NagendranDepartment of Clinical Sciences, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-8705-8576
Julie A NettifeeDepartment of Clinical Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Dani CarterDepartment of Clinical Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Karen R MuñanaDepartment of Clinical Sciences, North Carolina State University, Raleigh, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-ictal (PI) clinical signs are a key defining stage of seizure manifestation in dogs. However, this phase remains poorly understood.

objectivesTo further characterize PI signs and their relation to other parts of a seizure, and understand the owner's perception of how PI signs affect the quality of life (QOL) of the dog. ANIMALS: Eight-seven dogs with a diagnosis of idiopathic epilepsy from a single institution.

methodsThe prospective questionnaire-based study surveying owners of dogs previously and newly diagnosed with idiopathic epilepsy.

resultsPost-ictal signs were identified in 79/87 dogs, 5/5 of dogs with focal seizures and 74/82 of dogs with generalized seizures. Median duration of PI signs was 30 minutes (range, 5-4320 minutes). The most common PI signs reported were disorientation (50/79) and wobbliness or clumsiness (49/79). Within a year, a change in PI signs was seen in 18/79 dogs. The administration of benzodiazepines was significantly associated with an increase in duration of PI signs (P = .04). Post-ictal signs had more impact on dogs' quality of life compared with ictal signs (P < .01). Groupings of co-existing PI signs identified included disorientation, blindness and deafness.

conclusionPost-ictal signs are a commonly reported aspect of seizures in dogs with idiopathic epilepsy, both in focal as well as generalized seizures. Co-existence of signs could provide some valuable insight into the relevance of this particular phase of a seizure. Owner-reported signs and documentation emphasize the need for a better understanding of PI signs in dogs with idiopathic epilepsy.

Indexed as

Dog DiseasesEpilepsySeizuresAnimalsAnticonvulsantsDogsFemaleMaleProspective StudiesQuality of LifeSurveys and QuestionnairesAnticonvulsantspost‐ictalquality of lifequestionnaireseizures

Identifiers

PMID39831473
PMCPMC11744365

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.