Evidence mapPaperPMID 39833711Full record

ArticleBMC medical imaging2025

Association between non-alcoholic fatty liver disease and progression of abdominal aortic aneurysm: a multicenter study.

Ximing Wang, Jingxiang Sun, Na Chang, Menghan Liu, Shuai Zhang

Abstract readMulticenter Study
In one paragraph

Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ximing Wang *Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324 Jingwu Road, Jinan, Shandong, 251200, China.
Jingxiang Sun *Department of Radiology, The First Affiliated Hospital of Shandong First Medical University, No.16766 Jingshi Road, Jinan, Shandong, 251200, China.
Na ChangDepartment of Medical Technology, Jinan Nursing Vocational College, No. 3636 Gangxi Road, Jinan, Shandong, 250021, China.
Menghan LiuDepartment of Health Management, The First Affiliated Hospital of Shandong First Medical University, No.16766 Jingshi Road, Jinan, Shandong, 251200, China.
Shuai ZhangDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324 Jingwu Road, Jinan, Shandong, 251200, China. z6321106@163.com.

Funding

Academic promotion programme of Shandong First Medical University no. 2019QL023Major Program of Scientific and Technical Innovation 2030 of China No. 2021ZD0200516-09-01National Natural Science Foundation of China no. 8187354, 82271993
6 · The paper itself

Abstract

backgroundThe purpose of our study was to investigate the association between non-alcoholic fatty liver disease (NAFLD) and abdominal aortic aneurysms (AAA) progression using non-enhanced computed tomography (CT) and CT angiography (CTA).

methodsPatients with AAA and age- and sex-matched healthy subjects who underwent abdominal CTA and non-enhanced CT examination between January 2015 and January 2023 from four hospitals were retrospectively analyzed. Patients with AAA were divided into progression (growth rate > 10 mL/year) and non-progression groups, as well as those with NAFLD and without NAFLD, based on abdominal CT results. The Kaplan-Meier and Cox regression were used to investigate the association between NAFLD and AAA progression.

resultsA total of 151 patients with AAA (mean age: 69.1 ± 10.5 years old, 133 men) were included, among which 66 patients (43.7%) had NAFLD. During a median of 10.7 months (6.0-76.0 months), 57 patients (37.7%) had AAA progression. The prevalence of NAFLD was significantly higher in the AAA group compared to the control group (43.7% vs. 31.1%, p = 0.024). Multivariable regression analysis revealed that the NAFLD was independently associated with AAA progression (HR, 4.28; 95% CI, 2.20-8.31; p < 0.001). The area under curve of combined NAFLD and AAA maximal diameter was 0.857 for predicting AAA progression.

conclusionsNAFLD on non-enhanced CT is an independent predictor of AAA progression. It can improve the diagnostic efficacy of predicting the progression of abdominal aortic aneurysms. CLINICAL TRIAL NUMBER: Not applicable. This research is a retrospective analysis.

Indexed as

Aortic Aneurysm, AbdominalNon-alcoholic Fatty Liver DiseaseAgedAged, 80 and overCase-Control StudiesComputed Tomography AngiographyDisease ProgressionFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsTomography, X-Ray ComputedAbdominal aortic aneurysmFatty liverGrowthMultidetector computed tomographyNon-alcoholic fatty liver disease

Identifiers

PMID39833711
PMCPMC11749205

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.