Evidence mapPaperPMID 39834522Full record

ReviewAlpha psychiatry2024

Adjunctive Intermittent Theta-Burst Stimulation for Schizophrenia: A Systematic Review and Meta-analysis of Randomized Double-Blind Controlled Studies.

Kai-Si Wen, Xin-Hu Yang, Nan Zhang, Si-Yuan Lin, Xing-Bing Huang, Todd Jackson, Yu-Tao Xiang, Wei Zheng

Abstract readReview
In one paragraph

Review in Alpha psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kai-Si WenClinical Medicine, Guangxi University of Traditional Chinese Medicine, Nanning, China.ORCID 0009-0004-4651-7600
Xin-Hu YangDepartment of Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.ORCID 0000-0002-3677-867X
Nan ZhangDepartment of Psychiatry, Beijing Haidian Psychological Rehabilitation Hospital, Beijing, China.ORCID 0009-0008-6067-8995
Si-Yuan LinClinical Medicine, Xinxiang Medical University, Xinxiang, China.ORCID 0009-0001-1305-8231
Xing-Bing HuangDepartment of Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.ORCID 0000-0002-2960-2502
Todd JacksonDepartment of Psychology, University of Macau, Macao SAR, China.ORCID 0000-0001-5086-7663
Yu-Tao XiangUnit of Psychiatry, Department of Public Health and Medicinal Administration, University of Macau, Macao SAR, China.ORCID 0000-0002-2906-0029
Wei ZhengDepartment of Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.ORCID 0000-0003-2371-4789

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In order to determine whether intermittent theta-burst stimulation (iTBS) is a viable adjunct treatment for schizophrenia, a meta-analysis of double-blind, randomized clinical trials (RCTs) was performed. Methods: Four independent researchers extracted and synthesized data from RCTs on adjunctive iTBS for patients suffering from schizophrenia. RevMan 5.3 software was used to calculate risk ratios (RRs) and standardized mean differences (SMDs) along with their 95% confidence intervals (CIs). Results: Fifteen RCTs involving 671 patients with schizophrenia were included. Adjunctive iTBS was significantly superior to sham interventions for improvement in overall psychopathology (SMD = -0.75, 95% CI: -1.10, -0.41, Conclusion: The use of iTBS in patients with schizophrenia appears to be effective in improving psychiatric symptoms and cognitive function. To substantiate these preliminary findings, future research involving larger participant cohorts is warranted.

Indexed as

cognitive functionIntermittent theta burst stimulationmeta-analysisschizophrenia

Identifiers

PMID39834522
PMCPMC11744375

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.