ReviewCureus2024
Factors Associated With the Development of Heart Failure Following Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Physiology-Guided Complete Revascularization in Older Patients With Myocardial Infarction: Three-Year Outcomes of a Randomized Clinical Trial.JAMA cardiology · 2025Article
- The Monocyte-to-Lymphocyte Ratio Exhibits A Superior Prognostic Value in Patients with Newly Diagnosed Acute Coronary Syndrome.Reviews in cardiovascular medicine · 2025Article
- Connexin-43 Protein Expression Pattern Analysis in Myocardial Infarction Tissues.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute coronary syndrome (ACS) remains a major global health burden, encompassing a spectrum of conditions from unstable angina to acute myocardial infarction. Despite advancements in early detection and management, ACS is often complicated by the development of heart failure. This systematic review and meta-analysis aimed to identify factors associated with the development of heart failure following acute coronary syndrome. A comprehensive search was conducted across PubMed, Embase, Cochrane Library, and Web of Science from January 2018 to November 2024. Studies evaluating clinical or biochemical predictors of heart failure development in adult patients with acute coronary syndrome were included. Out of the initially identified studies, nine studies met the inclusion criteria. The Newcastle-Ottawa Scale was used to assess the quality of included studies, with most studies demonstrating high quality. The pooled analysis revealed that older age, female sex, diabetes, hypertension, chronic obstructive pulmonary disease, atrial fibrillation, multivessel coronary disease, and reduced left ventricular ejection fraction were significant predictors of heart failure development following acute coronary syndrome. The presence of atrial fibrillation emerged as the strongest predictor, followed by reduced left ventricular ejection fraction and chronic obstructive pulmonary disease. While complete revascularization showed a protective trend, this association did not reach statistical significance. The findings were limited by the predominantly retrospective nature of included studies and heterogeneity in the assessment of certain risk factors. Future research should focus on prospective studies with larger cohorts and comprehensive evaluation of additional factors such as treatment delays and revascularization strategies. Understanding these predictors can facilitate early risk stratification and guide targeted interventions, potentially improving outcomes for patients with acute coronary syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.