Evidence map›Paper›PMID 39835150›Full record

ArticleFrontiers in neurology2024

Efficacy of onabotulinumtoxinA treatment in episodic migraine.

Jasem Al-Hashel, Raed Alroughani, Malak Almojel, Samar Farouk Ahmed

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jasem Al-HashelDepartment of Neurology, Ibn Sina Hospital, Safat, Kuwait.
Raed AlroughaniDivision of Neurology, Amiri Hospital, Sharq, Kuwait.
Malak AlmojelDivision of Neurology, Amiri Hospital, Sharq, Kuwait.
Samar Farouk AhmedDepartment of Neurology, Ibn Sina Hospital, Safat, Kuwait.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: OnabotulinumtoxinA (BoNT-A) is approved as a prophylactic treatment of chronic migraine (CM) only. We aimed to assess the efficacy and safety of BoNT-A in the treatment of episodic migraine (EM). Methods: This is a prospective study included migraine patients, aged 18-65 years, and completed 1 year treatment with BoNT-A. Patients received 4 courses of BoNT-A treatment. Patient's headache was assessed by headache diary at baseline, and before every injection. Migraine Specific Quality of Life Questionnaire (MSQ) and work productivity were collected at baseline and in their last visit. Adverse events (AEs) were reported. Results: The study recruited 210 patients. Between baseline and the final visit, there were a significant reduction in migraine days, analgesic consumption days, and headache severity (9.54 ± 1.70 versus 4.58 ± 2.77, Conclusion: BoNT-A is an effective and well tolerated therapy in the prophylaxis of EM. It improved MSQ and WPAI.

Indexed as

botulinum toxin-Aepisodic migraineheadachemigraine-specific quality of lifeproductivity and activity impairment

Identifiers

PMID39835150
PMCPMC11743261

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.