Relationship Between Novel Inflammatory Indices and the Incidence of Postoperative Pneumonia After Endovascular Embolization for Aneurysmal Subarachnoid Hemorrhage.

Background: Accurate identification of the risk of postoperative pneumonia (POP) in aneurysmal subarachnoid hemorrhage (aSAH) is essential for the implementation of stratified treatment. This study evaluated the relevance and utility of the Systemic Immuno-inflammatory Index (SII) and the Systemic Inflammatory Response Index (SIRI) in predicting pneumonia after aSAH. Methods: Two hundred and forty patients undergoing aSAH intervention were included. Differences in SII and SIRI between patient groups were analyzed by propensity score matching (PSM). Receiver Operating Characteristic curves (ROC) were used to evaluate the predictive validity of SII and SIRI and to determine their predictive thresholds. The association of these indices with POP risk was assessed by multivariate logistic regression and restricted cubic spline (RCS), and subgroup analyses were performed. Results: The overall POP prevalence was 60%, with 37.5% males and 62.5% females. PSM analyses showed statistically significant differences between the two groups for SII ( Conclusion: This study reveals the potential role of SII and SIRI in predicting the risk of postoperative pneumonia in patients with aSAH, and provides a strong basis for early identification and stratification of patients who are at high risk of postoperative pneumonia in aSAH.