Evidence map›Paper›PMID 39836228›Full record

ArticleClinical oral investigations2025

Clinical and imaging aspects associated with persistent apical periodontitis: subsides for the treatment decision-making process.

Igor Bassi Ferreira Petean, Hugo Gaêta-Araujo, Jardel Francisco Mazzi-Chaves, Alice Correa Silva-Sousa, Fabiane Carneiro Lopes-Olhê, Francisco Wanderley Garcia de Paula-Silva, Manoel Damião de Sousa-Neto

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Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  7. Genetic Analysis ofGenes · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Igor Bassi Ferreira PeteanDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Hugo Gaêta-AraujoDepartment of Stomatology, Public Oral Health and Forensic Dentistry, Division of Oral Radiology, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Jardel Francisco Mazzi-ChavesDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Alice Correa Silva-SousaDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Fabiane Carneiro Lopes-OlhêDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Francisco Wanderley Garcia de Paula-SilvaDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.
Manoel Damião de Sousa-NetoDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. sousanet@forp.usp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 33002029032P4Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/21130-3
6 · The paper itself

Abstract

objectivesTo evaluate cases of persistent apical periodontitis (PAP) and what are the imaging and clinical aspects that could be considered in the PAP diagnosis and in their treatment decision-making process. METHODOLOGY: 423 patients with apical periodontitis at the time of non-surgical root canal treatment (NSRCT) were followed-up for at least 1 year. Periapical radiographic images were used to compare and determine periapical status at each time using the PAI scoring system. Cases scored as PAI 5 at the follow-up appointment were evaluated by CBCT, using the CBCTPAI scoring system. Associated, the data from imaging exams and from clinical evaluation were considered to make a decision for PAP treatment.

resultsRegarding sample composition, it was observed an association with ethnicity and PAP (p = 0.045). After follow-up, cases classified as PAI Score 1 and 2 and absence of symptoms/complaint were classified as successful. Cases classified as PAI Score 3 and absence of symptoms/complaint were referred for new follow-up visits until complete resolution of PAP. Cases scored as PAI 4 with clinical symptoms were indicated for non-surgical root canal retreatment. Cases scored as PAI 5 were assessed by CBCT, and in the presence of symptoms/complaint and a CBCTPAI score 3 were related to non-surgical root canal retreatment, while CBCTPAI scores 4 and 5 were refereed for endodontic surgery.

conclusionsClinical data, PAI and CBCTPAI scoring systems from image exams can be useful for PAP diagnosis and their treatment. CLINICAL RELEVANCE: In the decision-making process, clinical and imaging data are fundamental for the choose of an ideal protocol for treating PAP.

Indexed as

Clinical Decision-MakingCone-Beam Computed TomographyDecision MakingPeriapical PeriodontitisRoot Canal TherapyAdultAgedFemaleHumansMaleMiddle AgedCBCTPAI scoreDecision-making processPAI scorePersistent apical periodontitis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.