Evidence map›Paper›PMID 39836741›Full record

Trial reportCirculation. Cardiovascular interventions2025

Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis: The OPTIMIS Trial.

Kirstine Nørregaard Hansen, Jens Trøan, Akiko Maehara, Manijeh Noori, Mikkel Hougaard, Julia Ellert-Gregersen, Karsten Tange Veien, Anders Junker, Henrik Steen Hansen, Jens Flensted Lassen and 1 more

Registry-linked trialAbstract readRandomized Controlled TrialComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Circulation. Cardiovascular interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04666584 (Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold In Coronary Artery Stenosis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04666584 naunknown statusnot on this map

Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold In Coronary Artery Stenosis

TypeinterventionalSponsorOdense University HospitalRan2020 to 2024Enrolled82ConditionsCoronary Artery Disease, Stable Angina, Coronary Artery Stenosis, Myocardial InfarctionArmsScoreFlex balloon, Device: standard non-compliant balloon
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bioresorbable Scaffolds: Ready for a Rematch?Current cardiology reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kirstine Nørregaard HansenDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0003-4457-1713
Jens TrøanDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0002-0929-8697
Akiko MaeharaColumbia University Medical Center/New York-Presbyterian Hospital and the Cardiovascular Research Foundation, NY (A.M.).ORCID 0000-0002-1910-8447
Manijeh NooriDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0003-1009-4808
Mikkel HougaardDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0001-5390-6912
Julia Ellert-GregersenDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0001-5985-5538
Karsten Tange VeienDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0002-3898-9331
Anders JunkerDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).
Henrik Steen HansenDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).
Jens Flensted LassenDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0001-7972-9192
Lisette Okkels JensenDepartment of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).ORCID 0000-0002-4838-2429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBioresorbable scaffolds (BRS) were developed to overcome limitations related to late stent failures of drug-eluting stents, but lumen reductions over time after implantation of BRS have been reported. This study aimed to investigate if lesion preparation with a scoring balloon compared with a standard noncompliant balloon minimizes lumen reduction after implantation of a Magmaris BRS assessed with optical coherence tomography and intravascular ultrasound.

methodsEighty-two patients with stable angina were randomized in a ratio of 1:1 to lesion preparation with a scoring balloon versus a standard noncompliant balloon before implantation of a Magmaris BRS. The primary end point was minimal lumen area at 6-month follow-up.

resultsFollowing Magmaris BRS implantation, minimal lumen area (6.4±1.6 versus 6.3±1.5 mm

conclusionsLesion preparation with a scoring balloon before implantation of a Magmaris BRS resulted in a significantly larger minimal lumen area after 6 months due to less negative remodeling compared with lesion preparation with a standard noncompliant balloon. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04666584.

Indexed as

Absorbable ImplantsAngina, StableAngioplasty, Balloon, CoronaryCoronary StenosisCoronary VesselsAgedCoronary AngiographyFemaleHumansMaleMiddle AgedProspective StudiesProsthesis DesignTime FactorsTomography, Optical CoherenceTreatment Outcomeabsorbable implantsangina, stabledrug-eluting stentstomography, optical coherenceultrasonography, interventional

Identifiers

PMID39836741
PMCPMC11748912

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.