Evidence map›Paper›PMID 39837545›Full record

SynthesisApplied clinical informatics2025

Pediatric Predictive Artificial Intelligence Implemented in Clinical Practice from 2010 to 2021: A Systematic Review.

Swaminathan Kandaswamy, Lindsey A Knake, Adam C Dziorny, Sean M Hernandez, Allison B McCoy, Lauren M Hess, Evan Orenstein, Mia S White, Eric S Kirkendall, Matthew J Molloy and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in Applied clinical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Swaminathan KandaswamyDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Lindsey A KnakeDivision of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States.
Adam C DziornyDepartment of Pediatrics, University of Rochester, Rochester, New York, United States.
Sean M HernandezPrimary Care, Miami Veteran's Affairs, Miami, Florida, United States.
Allison B McCoyDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
Lauren M HessPediatric Hospital Medicine, Texas Children's Hospital, Houston, Texas, United States.
Evan OrensteinDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Mia S WhiteWoodruff Health Sciences Center Library, Emory University, Atlanta, Georgia, United States.
Eric S KirkendallDepartment of Pediatrics, Wake Forest University School of Medicine, Center for Healthcare Innovation, Winston-Salem, North Carolina, United States.
Matthew J MolloyDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.
Philip A HagedornDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.
Naveen MuthuDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Avinash MuruganDepartment of Internal Medicine, Yale New Haven Hospital, New Haven, Connecticut, United States.
Jonathan M BeusDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Mark MaiDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Brooke LuoDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States.
Juan D ChaparroDivision of Clinical Informatics, Department of Pediatrics, Nationwide Children's Hospital/Ohio State University College of Medicine, Columbus, Ohio, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To review pediatric artificial intelligence (AI) implementation studies from 2010 to 2021 and analyze reported performance measures.We searched PubMed/Medline, Embase CINHAL, Cochrane Library CENTRAL, IEEE, and Web of Science with controlled vocabulary. Inclusion criteria: AI intervention in a pediatric clinical setting that learns from data (i.e., data-driven, as opposed to rule-based) and takes actions to make patient-specific recommendations; published between 01/2010 and 10/2021; must have agency (AI must provide guidance that affects clinical care, not merely running in the background). We extracted study characteristics, target users, implementation setting, time span, and performance measures.Of 126 articles reviewed as full text, 17 met inclusion criteria. Eight studies (47%) reported both clinical outcomes and process measures, six (35%) reported only process measures and two (12%) reported only clinical outcomes. Five studies (30%) reported no difference in clinical outcomes with AI, four (24%) reported improvement in clinical outcomes compared with controls, two (12%) reported positive effects on clinical outcomes with use of AI but had no formal comparison or controls, and one (6%) reported poor clinical outcomes with AI. Twelve studies (71%) reported improvement in process measures, while two (12%) reported no improvement. Five (30%) studies reported on at least 1 human performance measure.While there are many published pediatric AI models, the number of AI implementations is minimal with no standardized reporting of outcomes, care processes, or human performance measures. More comprehensive evaluations will help elucidate mechanisms of impact.

Indexed as

Artificial IntelligencePediatricsChildHumans

Identifiers

PMID39837545
PMCPMC12119141

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.