Evidence map›Paper›PMID 39837970›Full record

ArticleScientific reports2025

PLK3 weakens antioxidant defense and inhibits proliferation of porcine Leydig cells under oxidative stress.

Chujie Chen, Jinyan He, Weixian Huang, Dong Xu, Zhaohui Li, Anqi Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chujie ChenDepartment of Laboratory Animal Science, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Jinyan HeDepartment of Laboratory Animal Science, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Weixian HuangDepartment of Laboratory Animal Science, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Dong XuDepartment of Biological and Environmental Engineering, Yueyang Vocational Technical College, Yueyang, Hunan, China.
Zhaohui LiXiangtan Livestock Breeding Station, Xiangtan, Hunan, China.
Anqi YangDepartment of Laboratory Animal Science, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China. yanganqi90@usc.edu.cn.

Funding

the Doc-toral Research Start-up Fund of University of South China 5524QD021the Excellent Youth Scholars of Hunan Provincial Department of Education 23B1097the Hengyang Municipal Agricultural Guidance Program 2023
6 · The paper itself

Abstract

Aging is characterized by cellular degeneration and impaired physiological functions, leading to a decline in male sexual desire and reproductive capacity. Oxidative stress (OS) lead to testicular aging by impairing the male reproductive system, but the potential mechanisms remain unclear. In the present study, the functional status of testicular tissues from young and aged boars was compared, and the transcriptional responses of Leydig cells (LCs) to hydrogen peroxide (H

Indexed as

AntioxidantsLeydig CellsOxidative StressProtein Serine-Threonine KinasesAnimalsCell ProliferationCellular SenescenceHydrogen PeroxideMaleProtein Interaction MapsSignal TransductionSwineAntioxidantsHydrogen PeroxideProtein Serine-Threonine KinasesLeydig cellsOxidative stressPLK3Transcriptome sequencing

Identifiers

PMID39837970
PMCPMC11751325

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.