Evidence map›Paper›PMID 39838077›Full record

ArticleScientific reports2025

Alterations of triple network dynamic connectivity and repetitive behaviors after mini-basketball training program in children with autism spectrum disorder.

Weike Zhang, Kelong Cai, Xuan Xiong, Lina Zhu, Zhiyuan Sun, Sixin Yang, Wei Cheng, Haiyong Mao, Aiguo Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weike ZhangNanjing Sport Institute, Nanjing, 210014, China.
Kelong CaiCollege of Physical Education, Yangzhou University, Yangzhou, 225127, China.
Xuan XiongDepartment of Physical Education, Nanjing University, Nanjing, 210093, China.
Lina ZhuCollege of Physical Education, Yangzhou University, Yangzhou, 225127, China.
Zhiyuan SunCollege of Physical Education, Yangzhou University, Yangzhou, 225127, China.
Sixin YangNantong Middle School, Nantong, 226001, China.
Wei ChengJiangsu Shipping College, Nantong, 226010, China.
Haiyong MaoCollege of Physical Education, Yangzhou University, Yangzhou, 225127, China.
Aiguo ChenNanjing Sport Institute, Nanjing, 210014, China. agchen@yzu.edu.cn.

Funding

Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX22_3419the National Social Science Foundation of China 23ATY008
6 · The paper itself

Abstract

Physical exercise has been demonstrated to effectively mitigate repetitive behaviors in children with autism spectrum disorder (ASD), but the underlying dynamic brain network mechanisms are poorly understood. The triple network model consists of three brain networks that jointly regulate cognitive and emotional processes and is considered to be the core network underlying the aberrant manifestations of ASD. This study investigated whether a mini-basketball training program (MBTP) could alter repetitive behaviors and the dynamic connectivity of the triple network. 28 male children with ASD were scanned twice with resting-state functional MRI and assessed for repetitive behaviors using the repetitive behavior scale (RBS-R). 15 children in the exercise group participated in a 12-week MBTP, while 13 in the control group maintained their regular routines. The feature of Dynamic independent component analysis (dyn-ICA) is its ability to capture the rate of change in connectivity between brain regions. In this study, it was specifically employed to examine the triple network dynamic connectivity in both groups. Compared to the control group, the exercise group exhibited distinct dynamic connectivity patterns in two networks: Network 1 involved cross-network dynamic connectivity changes within the triple network, and Network 2 pertained to dynamic connectivity alterations within the default mode network. Furthermore, a reduction in the RBS-R Total score was observed in the exercise group, reflecting improvements in self-injurious behavior and restricted behavior. Correlation analysis revealed that the amelioration of repetitive behaviors was associated with enhanced dynamic connectivity in parts of the triple network. These findings suggest that MBTP can improve repetitive behaviors in ASD children and is linked to changes in triple network dynamic connectivity.

Indexed as

Autism Spectrum DisorderBrainExerciseNerve NetStereotyped BehaviorBrain MappingChildHumansMagnetic Resonance ImagingMaleAutism spectrum disorderDynamic independent component analysisPhysical exerciseTriple network

Identifiers

PMID39838077
PMCPMC11751186

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.