Evidence mapPaperPMID 39838985Full record

ReviewQuantitative imaging in medicine and surgery2025

Methods for tissue perfusion assessment after Dellon decompression of tarsal tunnels in diabetic neuropathy: key to effective management-a narrative review.

Sofija Pejkova, Nevena Manevska, Sofija Tusheva, Gordana Georgieva, Blagoja Srbov, Ersin Vrajnko, Savetka Paljoskovska Jordanova, Tanja Makazlieva, Sinisa Stojanovski, David Scott Nickerson and 1 more

Abstract readReview
In one paragraph

Review in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Plastic and reconstructive surgery. Global open · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sofija PejkovaUniversity Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.ORCID https://orcid.org/0000-0002-6833-7078
Nevena ManevskaInstitute of Pathophysiology and Nuclear Medicine, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Sofija TushevaUniversity Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.ORCID https://orcid.org/0000-0001-8275-5260
Gordana GeorgievaUniversity Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Blagoja SrbovUniversity Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Ersin VrajnkoUniversity Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Savetka Paljoskovska JordanovaUniversity Clinic for Cardiology, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Tanja MakazlievaInstitute of Pathophysiology and Nuclear Medicine, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
Sinisa StojanovskiInstitute of Pathophysiology and Nuclear Medicine, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, Republic of North Macedonia.
David Scott NickersonWound Care Clinic, Sheridan Memorial Hospital, Sheridan, WY, USA.
A Lee DellonDivision of Plastic Surgery, Johns Hopkins University, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Diabetic neuropathy significantly elevates the risk of foot ulceration and lower-limb amputation, underscoring the need for precise assessment of tissue perfusion to optimize management. This narrative review explores the intricate relationship between sympathetic nerves and tissue perfusion in diabetic neuropathy, highlighting the important role of autonomic neuropathy in blood flow dynamics and subsequent compromises in tissue perfusion. The consequences extend to the development of diabetic peripheral neuropathy and related foot complications. By analyzing both non-invasive diagnostic methods and surgical interventions, such as tarsal tunnel decompression, the paper seeks to highlight their effectiveness in improving tissue perfusion, preventing ulcers, and reducing the risk of amputations in patients with diabetic peripheral neuropathy. Methods: We reviewed current literature on both non-invasive diagnostic tools and surgical techniques for assessing and improving tissue perfusion in diabetic neuropathy. Methods discussed include transcutaneous oxygen pressure (TcPO Key Content and Findings: Emphasizing the critical importance of surgical interventions, such as tarsal tunnel decompression and neurolysis of the posterior tibial nerve, the article underscores their efficacy in enhancing tissue perfusion and preventing ulcers and amputations. Additionally, it addresses the significance of precise blood flow measurement and timely intervention in the management of diabetic neuropathy and foot ulcers. The non-invasive techniques for assessing tissue perfusion and blood flow in diabetic neuropathy such as TcPO Conclusions: In conclusion, surgical interventions, both vascular and peripheral nerve are pivotal for optimizing patient care. Early identification of foot ulcers and peripheral arterial disease is imperative, and an understanding of blood flow dynamics, combined with effective surgical techniques, constitutes key elements in managing diabetic neuropathy, healing and preventing ulcers, and limb salvage.

Indexed as

blood flow assessmentdiabetic foot ulcers (DFU)Diabetic neuropathytissue perfusion

Identifiers

PMID39838985
PMCPMC11744174

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.