Evidence map›Paper›PMID 39840243›Full record

ReviewFood science of animal resources2025

Cultured Chinese Giant Salamander Skin and Skin Secretions as a Source of Bioactive Peptides for Food and Medicine.

Jinghua Wang, Yuchen Liu, Hongfei Guo, Dejing Chen, Hassan Idris Abdu, Meng Yang, Jinjin Pei, A M Abd El-Aty

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Food science of animal resources, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinghua WangHanzhong Science and Technology Resources Coordination Center, Hanzhong 723000, China.ORCID https://orcid.org/0009-0004-7466-945X
Yuchen LiuShaanxi Province Key Laboratory of Bioresources, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Qinba State Key Laboratory of Biological Resources and Ecological Environment, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID https://orcid.org/0009-0004-3737-1697
Hongfei GuoShaanxi Province Key Laboratory of Bioresources, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Qinba State Key Laboratory of Biological Resources and Ecological Environment, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID https://orcid.org/0009-0000-9207-2164
Dejing ChenShaanxi Province Key Laboratory of Bioresources, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Qinba State Key Laboratory of Biological Resources and Ecological Environment, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID https://orcid.org/0000-0003-0985-710X
Hassan Idris AbduCollege of Health Management, Shangluo University, Shangluo 726000, China.ORCID https://orcid.org/0000-0002-4784-939X
Meng YangShaanxi Province Key Laboratory of Bioresources, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Qinba State Key Laboratory of Biological Resources and Ecological Environment, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID https://orcid.org/0009-0007-4710-3209
Jinjin PeiShaanxi Province Key Laboratory of Bioresources, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C., Qinba State Key Laboratory of Biological Resources and Ecological Environment, College of Bioscience and Bioengineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID https://orcid.org/0000-0003-1301-3620
A M Abd El-AtyDepartment of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID https://orcid.org/0000-0001-6596-7907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphibians are enjoyable globally for their culinary value and are increasingly considered alternative protein sources. However, the skin of edible amphibians, especially giant salamanders, is often discarded without much thought. However, this underutilized resource holds significant potential for yielding valuable proteins and bioactive peptides (BPs). These peptides, such as brevinins, bombesins, dermaseptins, esculentins, magainins, temporins, tigerinins, and salamandrins, possess a wide range of biological activities, including antioxidant, antimicrobial, anticancer, and antidiabetic properties. This review provides a comprehensive analysis of the various BPs derived from giant salamander skin or secretions and their associated biological functions. Furthermore, it examines the nutritional composition of giant salamanders, their production status, and the challenges surrounding the use of their skin and secretions. This review also explores the potential applications of these BPs in the food and biomedical industries, particularly as multifunctional food additives, dietary supplements, and drug delivery agents.

Indexed as

bioactive peptidesbiomedical applicationsculinary appealgiant salamanderprotein source

Identifiers

PMID39840243
PMCPMC11743832

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.