Evidence mapPaperPMID 39841371Full record

ReviewAdvances in therapy2025

Improving Therapeutic Adherence and Reducing Therapeutic Inertia in the Management of People with Cardiometabolic Diseases: A Call-to-Action from the Middle East.

Wael Almahmeed, Zainab Alabadla, Fatheya Al Awadi, Dalal Alrohmaihi, Mostafa AlShamiri, Hussein Elbadawi, Hassan El-Tamimi, Abdel-Nasser Elzouki, Mohamed Farghaly, Khadija Hafidh and 5 more

Abstract readReview
In one paragraph

Review in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wael AlmahmeedCleveland Clinic Abu Dhabi, Hamouda Bin Ali Al Dhaheri Street, Abu Dhabi, United Arab Emirates. wmahmeed@gmail.com.
Zainab AlabadlaDiabetes and Endocrine Department, Al Jalila Children's Hospital, Dubai, United Arab Emirates.
Fatheya Al AwadiEndocrine Department, Dubai Hospital, Dubai, United Arab Emirates.
Dalal AlrohmaihiAwali Hospital, Awali, Bahrain.
Mostafa AlShamiriCardiac Sciences Department, College of Medicine and University Medical City King Saud University, Riyadh, Kingdom of Saudi Arabia.
Hussein ElbadawiMetabolic Unit, Myclinic International, Jeddah, Kingdom of Saudi Arabia.
Hassan El-TamimiCardiology Department, Mediclinic Parkview Hospital, Dubai, United Arab Emirates.
Abdel-Nasser ElzoukiGeneral Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
Mohamed FarghalyDubai Medical College, Dubai, United Arab Emirates.
Khadija HafidhMohamed Bin Rashid College of Medicine and Health Sciences, Dubai, United Arab Emirates.
Mohamed HassaneinEndocrine Department, Dubai Hospital, Dubai, United Arab Emirates.
Adel Khalifa HamadMohammed Bin Khalifa Al Khalifa Cardiac Centre, Awali, Bahrain.
Kamlesh KhuntiDiabetes Research Centre, University of Leicester, Leicester, UK.
Hani SabbourMediclinic Airport Road Hospital, Abu Dhabi, United Arab Emirates.
Aletta E SchutteSchool of Population Health, University of New South Wales, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension, dyslipidemia, and type 2 diabetes are highly prevalent and poorly controlled cardiometabolic diseases in the Middle East. Therapeutic non-adherence and therapeutic inertia are major contributors to this suboptimal disease control. Regardless of the cardiometabolic disease, evidence-based solutions may be used to improve therapeutic non-adherence and overcome inertia, and thereby help to alleviate the heavy burden of cardiovascular disease in the Middle East. Such solutions include the routine and early use of single-pill combinations, educational initiatives for patients, and multidisciplinary team-based care. This article highlights these and other potential solutions for therapeutic non-adherence and inertia, as discussed at the 2024 Evidence in the Cardiometabolic Environment (EVIDENT) Summit. There is now a 'call-to-action' from healthcare providers and other stakeholder groups to ensure that the solutions discussed at this meeting are implemented within health systems in the Middle East to significantly improve cardiovascular outcomes.Infographic available for this article.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2DyslipidemiasHypertensionMedication AdherenceHumansMiddle EastDyslipidemiaHypertensionTherapeutic adherenceTherapeutic inertiaType 2 diabetes

Identifiers

PMID39841371
PMCPMC11868338

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.