Evidence map›Paper›PMID 39841921›Full record

ReviewAccounts of chemical research2025

Bistable Functions and Signaling Motifs in Systems Chemistry: Taking the Next Step Toward Synthetic Cells.

Indrajit Maity, Nathaniel Wagner, Dharm Dev, Gonen Ashkenasy

Abstract readReview
In one paragraph

Review in Accounts of chemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Indrajit MaityDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er Sheva 84105, Israel.
Nathaniel WagnerDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er Sheva 84105, Israel.
Dharm DevDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er Sheva 84105, Israel.
Gonen AshkenasyDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er Sheva 84105, Israel.ORCID 0000-0003-0076-437X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key challenge in modern chemistry research is to mimic life-like functions using simple molecular networks and the integration of such networks into the first functional artificial cell. Central to this endeavor is the development of signaling elements that can regulate the cell function in time and space by producing entities of code with specific information to induce downstream activity. Such artificial signaling motifs can emerge in nonequilibrium systems, exhibiting complex dynamic behavior like bistability, multistability, oscillations, and chaos. However, the

Indexed as

Artificial CellsSignal TransductionPeptidesPeptides

Identifiers

PMID39841921
PMCPMC11800382

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.