ArticleRenal failure2025
Higher serum Metrnl levels are associated with increased vascular calcification in hemodialysis patients.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Advances in the clinical applications of sodium thiosulphate.Annals of medicine · 2026Review
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Abstract
backgroundMeteorin-like (Metrnl) is a newly identified secreted protein that plays important roles in metabolic and inflammation-related diseases. Our study aimed to evaluate serum Metrnl levels and establish their relationship with vascular calcification (VC) in hemodialysis (HD) patients.
methodsIn total, 313 HD patients and 41 healthy individuals, as controls, were included. Serum levels of Metrnl and other clinical and laboratory parameters were compared. VC was evaluated based on the abdominal aortic calcification (AAC) scores. HD patients were divided into a high-AAC score group (AAC score ≥ 4) and a low-AAC score group (AAC score < 4).
resultsHD patients had higher serum Metrnl levels than the controls (0.52 ± 0.26 ng/ml vs. 0.24 ± 0.11 ng/ml,
conclusionThe results herein provide the first clinical evidence of the association between serum Metrnl and VC in HD patients. Higher Metrnl levels, older age, diabetes mellitus, and higher serum
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