Evidence map›Paper›PMID 39843371›Full record

ArticleBMJ open2025

Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers.

Runfeng Shi, Huilin Cao, Meixin He, Yuyu Wang, Yue Zhu, Xinyu Wang, Caizhen You, Liming Liang, Xu Xia

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Runfeng ShiThe First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0009-0001-2149-1078
Huilin CaoThe First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong, China.
Meixin HeSchool of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Yuyu WangThe First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong, China.
Yue ZhuCollege of Acupuncture-Moxibustion and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Xinyu WangSchool of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Caizhen YouThe First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong, China.
Liming LiangLibrary, Southern Medical University, Guangzhou, Guangdong, China.
Xu XiaLibrary, Southern Medical University, Guangzhou, Guangdong, China 853877559@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCOVID-19, a public health emergency affecting the world in 2019, not only greatly promoted the development and application of vaccines but also effectively shortened the publishing time of scientific papers. In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014-2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.

designBibliometric analysis through data analysis and visual mapping. DATA SOURCES: Scientific articles. DATA EXTRACTION AND SYNTHESIS: 'Vaccine' and 'vaccines' were used in the WoS database to retrieve the publications and to adequately collect the data; Microsoft Excel was used for data analysis; and VOSviewer was used for visual description of data. Overall publication trends, countries, institutions and funding agencies, authors and articles, journals and languages, and research areas and co-occurrence keywords were analysed by bibliometrics.

resultsA total of 3258 highly cited papers were published in the field of vaccines in the past decade, from 735 different journals. With the COVID-19 pandemic in 2019, the number of highly cited papers in the field of vaccine research increased significantly from 2020 to 2024, accounting for 76.12%. The number of highly cited papers for vaccines peaked in 2021 and 2022, followed by a rapid decline. Highly cited papers came from 7133 institutions in 153 countries, and the most influential country in the field of vaccines was the USA, which published 1733 highly cited papers, accounting for 53.19% of the highly cited papers. The top 15 institutions with the largest influence were all from the USA or UK with 2567 published papers in total, accounting for 78.79% of highly cited papers. 4787 funding agencies were recognised in funding 2368 highly cited papers. A total of 30 926 authors in 90 research areas contributed significantly to global vaccine research. The most highly cited paper was 'Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine' from the

conclusionsThis study visualised the research and application of vaccines in the world from the perspective of papers output, drew the knowledge map and identified the important research hotspots and development trends in the vaccine field in the recent 10 years (2014-2024), which is helpful for Centres for Disease Control and Prevention, clinicians, researchers and health policymakers to better understand the research status and problems in vaccine research and application and predict its future development direction.

Indexed as

BibliometricsBiomedical ResearchCOVID-19COVID-19 VaccinesGlobal HealthHumansPandemicsSARS-CoV-2COVID-19 VaccinesBIOTECHNOLOGY & BIOINFORMATICSCOVID-19Public healthVaccination

Identifiers

PMID39843371
PMCPMC11784126

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.