Evidence map›Paper›PMID 39843493›Full record

Trial reportScientific reports2025

Enhancing social functioning using multi-user, immersive virtual reality.

D J Holt, N R DeTore, B Aideyan, L Utter, L Vinke, D S Johnson, J Zimmerman, K N Dokholyan, A Burke

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06360562 (Reconnecting to Ourselves and Others in Virtual Meetings), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06360562 naactive not recruitingnot on this map

Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)- Resilience Training in Virtual Reality

TypeinterventionalSponsorMassachusetts General HospitalRan2020 to 2028Enrolled174ConditionsMood Disorders, Anxiety Disorders, Psychotic DisordersArmsResilience Training
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Transdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Transdiagnostic prevention in youth mental health, Part II: interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D J Holt *Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA. dholt@mgh.harvard.edu.
N R DeTore *Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
B AideyanDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
L UtterDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
L VinkeDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
D S JohnsonDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
J ZimmermanDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
K N DokholyanDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.
A BurkeDepartment of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rates of loneliness and other forms of social disconnection have been increasing worldwide. Prior studies have suggested that brief behavioral interventions can teach skills that may improve social functioning and connection but, currently, access to such interventions is limited. One previously untested approach for addressing this gap is to teach these skills using immersive, multi-user virtual reality (VR). To measure the feasibility of this approach, 33 young adults experiencing social discomfort were enrolled in a study of a VR-based application called Reconnecting with Ourselves and Others in virtual Meetings (ROOM), which delivered a previously validated, mindfulness-based intervention. Satisfaction ratings, qualitative feedback, and quantitative measures of aspects of social functioning, including social comfort, interpersonal distance, and facial affect recognition, were collected from participants. All of the participants attended more than half of the sessions and 90.3% found ROOM to be beneficial and useful. In addition, comfort with others in the real world (p = 0.02) and facial affect recognition accuracy (p = 0.02) significantly increased, while interpersonal distances remained unchanged, following ROOM. An immersive, multi-user VR intervention may represent one feasible, scalable approach for disseminating skills that can improve social functioning and connection. Trial registration Clinicaltrial.org # NCT06360562.

Indexed as

Virtual RealityAdolescentAdultFemaleHumansInterpersonal RelationsLonelinessMaleMindfulnessYoung Adult

Identifiers

PMID39843493
PMCPMC11754853

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.