Evidence mapPaperPMID 39844396Full record

ReviewMedicinal chemistry (Shariqah (United Arab Emirates))2025

Exploring the Therapeutic Potential of 1,3-Thiazole: A Decade Overview.

Ajit Manchare, Swapnali Parit, Mukta Lele, Navnath Hatvate

Abstract readReview
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In one paragraph

Review in Medicinal chemistry (Shariqah (United Arab Emirates)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ajit ManchareDepartment of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, Marathwada Campus, Jalna-431203, Maharashtra, India.
Swapnali ParitDepartment of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, Marathwada Campus, Jalna-431203, Maharashtra, India.
Mukta LeleDepartment of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, Marathwada Campus, Jalna-431203, Maharashtra, India.
Navnath HatvateDepartment of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, Marathwada Campus, Jalna-431203, Maharashtra, India.ORCID 0000-0002-3388-3247

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The escalating prevalence of lifestyle and microbial diseases poses a significant threat to human well-being, necessitating the discovery and development of novel drugs with distinct modes of action. Addressing this challenge involves employing innovative strategies, and one current approach involves utilizing heterocyclic compounds to synthesize hybrid molecules. These hybrids have resulted from the fusion of two or more bioactive heterocyclic moieties into a single molecule. The focus of this review revolves around the strategic incorporation of heterocycles, particularly thiazole derivatives. Thiazole derivatives, due to their unique structural features, are explored in depth within this review paper. The paper comprehensively outlines diverse hybridization strategies of thiazole derivatives, highlighting their vibrant biological activities mainly in the last decade, 2014-2024. By presenting an extensive overview, the review aims to provide valuable insights into the potential of thiazole derivatives as promising candidates for drug development. The insights garnered from this paper are expected to offer valuable guidance for future drug design endeavors, providing a foundation for developing novel and effective drugs to combat lifestyle diseases and microbial resistance.

Indexed as

Anti-Bacterial AgentsThiazolesAnimalsHumansMolecular StructureAnti-Bacterial AgentsThiazoles13-thiazolesanti-Alzheimer agentsanti-cancer agentsanti-diabetic agentsanti-fungal agentsanti-microbial agentsanti-protozoal agents.anti-seizure agents

Identifiers

PMID39844396

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.