Evidence map›Paper›PMID 39844555›Full record

ReviewCurrent gene therapy2025

Molecular Insights into RNA Modifications and Their Role in Shaping Immune Responses and Tumor Microenvironments.

Ashiq Ali, Tehreem Ajmal, Aisha Khatoon, Kaynaat Akbar, Urooj Irshad, Bilal Murtaza, Ziyi Ji, Abdullah Ali, Qaisar Tanveer, Zhongjing Su

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gene therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashiq AliDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Tehreem AjmalInstitute of Microbiology, University of Agriculture Faisalabad, Pakistan.
Aisha KhatoonDepartment of Pathology, University of Agriculture Faisalabad, Pakistan.
Kaynaat AkbarDepartment of Zoology, Wildlife and Fisheries, Faculty of Sciences, University of Agriculture, Faisalabad 38040, Punjab, Pakistan.
Urooj IrshadDepartment of Zoology, Superior University, Lahore, Pakistan.
Bilal MurtazaSchool of Bioengineering, Dalian University of Science and Technology, Dalian, China.
Ziyi JiDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Abdullah AliDepartment of Theriogenology, University of Agriculture, Faisalabad, Pakistan.
Qaisar TanveerThe Roslin Institute, The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, EH25 9RG, UK.
Zhongjing SuDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA modifications play crucial roles in immune system development and function, with dynamic changes essential for diverse cellular processes. Innovative profiling technologies are invaluable for understanding the significance of these modifications in immune cells, both in healthy and diseased states. This review explores the utility of such technologies in uncovering the functions of RNA modifications and their impact on immune responses. Additionally, it delves into the mechanisms through which aberrant RNA modifications influence the tumor microenvironments immune milieu. Despite significant progress, several outstanding research questions remain, highlighting the need for further investigation into the molecular mechanisms underlying RNA modification's effects on immune function in various contexts.

Indexed as

NeoplasmsRNARNA Processing, Post-TranscriptionalTumor MicroenvironmentAnimalsHumansRNAdiverse cellular processesimmune cells.immune responsesimmune system developmentRNA modificationstumor microenvironment

Identifiers

PMID39844555

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.