ArticleFrontiers in molecular biosciences2024
Lipopolysaccharide affects metabolic processes and energy homeostasis in the corpus luteum.
Article in Frontiers in molecular biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- PET microplastics induce lipotoxicity in the porcine pancreas.BMC genomics · 2026Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chronic inflammation caused by Methods: The aim of this study was to determine the in vitro effects of lipopolysaccharide (LPS) on the proteomic profile of the porcine CL in the mid-luteal phase of the estrous cycle using LC-MS/MS analysis. The CL slices were incubated in the presence of LPS for 24 h. Results: We identified 12 differentially regulated proteins after treatment with LPS (7 of them were upregulated, while 5 were downregulated). The analysis showed that these proteins are involved in processes such as glucose metabolism, the tricarboxylic acid cycle (TCA), detoxification processes as well as steroid biosynthesis in the CL. Moreover, we demonstrated that LPS decreases glucose levels and increases progesterone levels in the CL. Conclusion: These findings suggest that LPS modulates key metabolic pathways in the CL, potentially impacting its functional activity.
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