Evidence map›Paper›PMID 39846217›Full record

ArticleInnate immunity

The imbalance of circulating PD-L1-expressing non-classical/ classical monocytes is involved in immunocompromised host related pulmonary opportunistic infection.

Danhong Zhou, Yujia Jin, Yifan Jin, Yu Shen, Qiuxia Qu, Cheng Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danhong ZhouDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China.
Yujia JinDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China.
Yifan JinDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China.
Yu ShenJiangsu Key Laboratory of Clinical Immunology, Soochow University, Suzhou, China.
Qiuxia QuJiangsu Key Laboratory of Clinical Immunology, Soochow University, Suzhou, China.
Cheng ChenDepartment of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-9583-7991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of biological therapy and glucocorticoids in Auto-immune diseases (AID) patients will cause immunocompromised host (ICH) prone to infection. And monocytes play a key role in both innate and adaptive immune responses. We aimed to investigate the changes of circulating monocyte subsets in AID or AID-ICH patients with pulmonary infection. The subgroups and PD-L1 expression of monocytes were measured by flow cytometry in healthy individuals (HC), new-onset AID patients (AID cohort) and AID-ICH patients with pulmonary opportunistic infection (AID-ICH cohort). Flow cytometry analysis was used to determine the distribution of monocyte subsets, including classical monocytes (CL, CD14

Indexed as

Autoimmune DiseasesB7-H1 AntigenImmunocompromised HostMonocytesOpportunistic InfectionsAdultAgedFemaleHumansLipopolysaccharide ReceptorsMaleMiddle AgedB7-H1 AntigenCD274 protein, humanLipopolysaccharide ReceptorsICHmonocytesopportunistic infectionPD-L1

Identifiers

PMID39846217
PMCPMC11774481

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.