Trial reportHospital pediatrics2025
Comparing Midline and Peripherally Inserted Central Catheters: A Randomized Feasibility Trial.
Trial report in Hospital pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- An international randomised controlled trial of a novel antimicrobial dressing for peripheral intravenous catheters (ProP trial).Antimicrobial resistance and infection control · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesThe most effective use of midline catheters in children is not understood. We aimed to (1) test the feasibility of a trial comparing peripherally inserted central catheters (PICCs) to midline catheters in hospitalized children in need of durable vascular access and (2) collect preliminary effectiveness data of the 2 devices.
methodsOur study combined a single site, randomized controlled feasibility trial (RCT, primary study) and a prospective observational study (alternative study) comparing PICCs to midline catheters. Hospitalized children aged 2 to 17 years in need of noncentral, medium-term vascular access (5-14 days) were enrolled for 1 year. The primary outcome of the RCT was a 4-measure feasibility outcome, and we had an enrollment goal of 30 participants/arm. Effectiveness outcomes (both studies) included time-to-device removal and all-cause failure.
resultsBetween August 2022 and August 2023, only 43 of 260 screened patients met eligibility criteria because of a decrease in eligible PICCs. A total of 35 patients were enrolled: 8 out of 10 in the RCT (4/arm) and 27 out of 33 in the alternative study (21 midline catheters, 6 PICCs). The RCT eligibility goal was not met. The other feasibility measures were met: (1) 80% of eligible patients enrolled, (2) 100% of eligible patients received the assigned intervention, (3) 96% of inserters found the study acceptable, and (4) there were no missing data.
conclusionsBecause of a decrease in PICC use for noncentral, medium-term vascular access needs, a trial comparing devices may not be practical for assessing the effective use of midline catheters in hospitalized children. Next steps may include a hybrid effectiveness-implementation study evaluating an intravenous catheter selection algorithm that incorporates midline catheters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.