Evidence map›Paper›PMID 39849151›Full record

Trial reportDiabetologia2025

Glucose Lowering through Weight management (GLoW): a randomised controlled trial of the clinical and cost effectiveness of a diabetes education and behavioural weight management programme vs a diabetes education programme in adults with a recent diagnosis of type 2 diabetes.

Julia Mueller, Penny Breeze, Francesco Fusco, Stephen J Sharp, Katharine Pidd, Alan Brennan, Andrew J Hill, Stephen Morris, Carly A Hughes, Sarah E Bates and 12 more

Abstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Julia MuellerMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK. Julia.Mueller@mrc-epid.cam.ac.uk.ORCID http://orcid.org/0000-0002-4939-7112
Penny BreezeSheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-4189-8676
Francesco FuscoDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5515-3977
Stephen J SharpMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2375-1440
Katharine PiddSheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0009-0007-7112-4763
Alan BrennanSheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-1025-312X
Andrew J HillSchool of Medicine, University of Leeds, Leeds, UK.ORCID http://orcid.org/0000-0003-3192-0427
Stephen MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-5828-3563
Carly A HughesMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9560-7873
Sarah E BatesSheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-6358-0060
Daniel PollardSheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0001-5630-0115
Jenny WoolstonMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-0127-2898
Emma LachassseigneMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5819-0845
Marie StubbingsMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Fiona WhittleMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5461-521X
Rebecca A JonesMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2197-1175
Clare E BoothbyMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9396-8333
Robbie DuschinskyDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2023-5328
Jennifer BostockPublic Involvement Lead, Quality Safety and Outcomes Policy Research Unit, University of Kent, Oxford and Leeds, Kent, UK.ORCID http://orcid.org/0000-0001-9261-9350
Nazrul IslamSchool of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0003-3982-4325
Simon J GriffinMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-2157-4797
Amy L AhernMRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5069-4758

Funding

Medical Research Council MC_UU_00006/6National Institute for Health and Care Research RP-PG-0216-20010NIHR Cambridge Biomedical Research Centre NIHR203312
6 · The paper itself

Abstract

aims/hypothesisUK standard care for type 2 diabetes is structured diabetes education, with no effects on HbA

methodsWe conducted a pragmatic, randomised, parallel two-group trial. Participants were adults (≥18 years) with overweight or obesity (BMI≥25 kg/m

resultsWe randomised 577 participants (DEW: 289, DE: 288); 398 (69%) completed 12 month follow-up. We found no evidence for an intervention effect on change in HbA CONCLUSIONS/

interpretationA commercial behavioural weight management programme combined with remote dietary counselling after diagnosis of type 2 diabetes did not improve HbA

trial registrationISRCTN 18399564

fundingNational Institute for Health and Care Research (NIHR; RP-PG-0216-20010), Medical Research Council (MC_UU_00006/6), NIHR Cambridge Biomedical Research Centre (NIHR203312).

Indexed as

Diabetes Mellitus, Type 2Patient Education as TopicWeight Reduction ProgramsAdultAgedBehavior TherapyBlood GlucoseCost-Benefit AnalysisCost-Effectiveness AnalysisFemaleGlycated HemoglobinHumansMaleMiddle AgedObesityWeight LossBlood GlucoseGlycated HemoglobinBehavioural weight managementDiabetes mellitus, type 2ObesityOverweightRandomised controlled trialWeight lossWeight reduction programmes

Identifiers

PMID39849151
PMCPMC12021704

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.