Evidence map›Paper›PMID 39850232›Full record

ArticleJournal of pharmaceutical analysis2024

Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS, ER stress, and blocked autophagy.

Yacong Ji, Chongyang Li, Sicheng Wan, Zhen Dong, Chaolong Liu, Leiyang Guo, Shaomin Shi, Mingxin Ci, Minghao Xu, Qian Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Sirtuins in mitophagy: key gatekeepers of mitochondrial quality.Molecular and cellular biochemistry · 2025
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yacong JiDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Chongyang LiDepartment of Medical Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Sicheng WanState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Zhen DongState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Chaolong LiuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Leiyang GuoDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Shaomin ShiDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Mingxin CiState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Minghao XuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Qian LiDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Huanrong HuDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Hongjuan CuiState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Yaling LiuDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetrandrine (TET), a natural bisbenzyl isoquinoline alkaloid extracted from

Indexed as

Cytoskeletal protein depolymerizationMelanomaMitophagyReactive oxygen species (ROS)Sirtuin 5 (SIRT5)Tetrandrine

Identifiers

PMID39850232
PMCPMC11755340

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.