Evidence map›Paper›PMID 39851546›Full record

ArticleCells2025

Neuroprotective Efficacy of

Yongjae Hong, Geon Ko, Yeong-Jae Jeon, Hyeon-Man Baek, Juni Lee, Donghun Lee, Jieun Park, Jaehong Kim, Keun-A Chang

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Review onPlants (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yongjae HongDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Geon KoDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Yeong-Jae JeonDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Hyeon-Man BaekDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Juni LeeDepartment of Herbal Pharmacology, College of Korean Medicine, Gachon University, Seongnam-si 13120, Republic of Korea.
Donghun LeeDepartment of Herbal Pharmacology, College of Korean Medicine, Gachon University, Seongnam-si 13120, Republic of Korea.ORCID 0000-0003-1075-0713
Jieun ParkDepartment of Neurology, College of Medicine, Dongguk University, Ilsan 10326, Republic of Korea.
Jaehong KimDepartment of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0001-5653-1159
Keun-A ChangDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0002-6157-6340

Funding

Gachon University research fund of 2023 GCU-202300600001National Research Foundation (NRF) of Korea 2020M3A9E4104384National Research Foundation (NRF) of Korea RS-2024-00354414
6 · The paper itself

Abstract

Stroke affects over 12 million people annually, leading to high mortality, long-term disability, and substantial healthcare costs. Although East Asian herbal medicines are widely used for stroke treatment, the pathways of operation they use remain poorly understood. Our study investigates the neuroprotective properties of

Indexed as

Anti-Inflammatory AgentsAntioxidantsAstragalus PlantIschemic StrokeNeuroprotective AgentsAnimalsCell SurvivalDisease Models, AnimalMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesAnti-Inflammatory AgentsAntioxidantsNeuroprotective AgentsReactive Oxygen SpeciesAstragalus mongholicusbrain injurycognitive impairmentphotothrombotic-induced mouse modelstroketransient middle cerebral artery occlusion

Identifiers

PMID39851546
PMCPMC11764225

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.