Evidence map›Paper›PMID 39852511›Full record

ReviewMarine drugs2024

The Effects of Astaxanthin on Metabolic Syndrome: A Comprehensive Review.

Chunhao Gao, Nengyun Gong, Fangtian Chen, Shiran Hu, Qingxin Zhou, Xiang Gao

Abstract readReview
In one paragraph

Review in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunhao GaoCollege of Life Sciences, Qingdao University, Qingdao 266071, China.
Nengyun GongCollege of Life Sciences, Qingdao University, Qingdao 266071, China.
Fangtian ChenDepartment of Marine Technology, Rizhao Polytechnic, Shandong Engineering and Technology Research Center for Marine Crustacean Resources Comprehensive Utilization, Shandong Engineering Research Center for Efficient Utilization Technology of Marine Food Resources, Rizhao Key Laboratory of Efficient Utilization of Marine Food Resources, Rizhao 276826, China.
Shiran HuCollege of Life Sciences, Qingdao University, Qingdao 266071, China.
Qingxin ZhouDepartment of Marine Technology, Rizhao Polytechnic, Shandong Engineering and Technology Research Center for Marine Crustacean Resources Comprehensive Utilization, Shandong Engineering Research Center for Efficient Utilization Technology of Marine Food Resources, Rizhao Key Laboratory of Efficient Utilization of Marine Food Resources, Rizhao 276826, China.
Xiang GaoCollege of Life Sciences, Qingdao University, Qingdao 266071, China.ORCID 0000-0002-4674-0317

Funding

Natural Science Foundation of Shandong Province ZR2024MC094Shandong Province Colleges and Universities "youth innovation technology plan" pro-ject 2019KJF014
6 · The paper itself

Abstract

Metabolic syndrome (MS) represents a complex cluster of metabolic disorders primarily characterized by obesity, insulin resistance, hyperglycemia, dyslipidemia, hypertension, and hyperuricemia. Diet and functional ingredients play a pivotal role in seeking non-pharmacological strategies to prevent and ameliorate MS. Astaxanthin (AST), a carotenoid found in various marine organisms, exhibits exceptional antioxidant properties and holds great promise as a natural compound that improves MS. This article introduces the basic properties of AST, including its absorptance and metabolic pathways, along with various isomers. Most importantly, we comprehensively review the effects and mechanisms of AST on improving the primary components of MS. These mechanisms primarily involve regulating signal transduction, transport, or metabolic pathways within the body, as well as influencing intestinal microbiota and metabolites, thereby exerting positive effects on metabolism and inhibiting the occurrence of MS. This review emphasizes the potential efficacy of AST in managing MS. However, more studies are needed to confirm the clinical effect of AST on MS and reveal potential molecular mechanisms.

Indexed as

Metabolic SyndromeAnimalsAntioxidantsAquatic OrganismsGastrointestinal MicrobiomeHumansXanthophyllsAntioxidantsastaxanthineXanthophyllsastaxanthindyslipidemiainsulin resistancemetabolic syndromeobesity

Identifiers

PMID39852511
PMCPMC11766962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.