Evidence map›Paper›PMID 39852971›Full record

ArticleToxins2025

Influence of

Mohamad Ayoub, Salma Fayjaloun, Rabih Roufayel, Dany El Obeid, Ziad Fajloun, Mohamad Rima, Marc Karam

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  4. Effect ofMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamad AyoubFaculty of Sciences, University of Balamand, Al-Kourah, P.O. Box 100, Tripoli 1300, Lebanon.ORCID 0009-0007-1604-5253
Salma FayjalounDepartment of Cell Culture, Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Applications, EDST, Lebanese University, Tripoli 1300, Lebanon.
Rabih RoufayelCollege of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait.ORCID 0000-0002-4595-1104
Dany El ObeidFaculty of Agriculture & Veterinary Sciences, Lebanese University, Dekwaneh, Beirut 2832, Lebanon.ORCID 0000-0002-1967-1918
Ziad FajlounDepartment of Cell Culture, Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Applications, EDST, Lebanese University, Tripoli 1300, Lebanon.ORCID 0000-0002-6502-3110
Mohamad RimaDepartment of Natural Sciences, Lebanese American University, Byblos P.O. Box 36, Lebanon.ORCID 0000-0002-0335-9882
Marc KaramFaculty of Sciences, University of Balamand, Al-Kourah, P.O. Box 100, Tripoli 1300, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperalgesia is a condition marked by an abnormal increase in pain sensitivity, often occurring in response to tissue injury, inflammation, or prolonged exposure to certain medications. Inflammatory mediators, such as cytokines IL-1β, IL-6, and TNF-α, play a central role in this process, amplifying pain perception. Developing effective treatments that address the underlying mechanisms of hyperalgesia is an active field of research.

Indexed as

Anti-Inflammatory AgentsBee VenomsCytokinesHyperalgesiaNociceptionAnimalsBeesDisease Models, AnimalFemaleFormaldehydeMaleMiceAnti-Inflammatory AgentsBee VenomsCytokinesFormaldehydeA. mellifera syriacabee venomcytokineshyperalgesiaimmunomodulatory activityinflammationpain

Identifiers

PMID39852971
PMCPMC11769041

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.