Evidence mapPaperPMID 39853716Full record

ReviewJournal of cellular and molecular medicine2025

Metrnl and Cardiomyopathies: From Molecular Mechanisms to Therapeutic Insights.

Miaomiao Xu, Xiaoguang Liu, Liming Lu, Zhaowei Li

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miaomiao XuSchool of Physical Education and Health, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xiaoguang LiuCollege of Sports and Health, Guangzhou Sport University, Guangzhou, Guangdong, China.ORCID 0000-0003-0183-2100
Liming LuSouth China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Zhaowei LiSchool of Physical Education and Health, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Funding

Guangdong Provincial Sports Bureau 2024-2025 Science and Technology Innovation and Sports Culture Development Research Project GDSS2024N010National Natural Science Foundation of China 32300964
6 · The paper itself

Abstract

Cardiomyopathies, a diverse group of diseases affecting the heart muscle, continue to pose significant clinical challenges due to their complex aetiologies and limited treatment options targeting underlying genetic and molecular dysregulations. Emerging evidence indicates that Metrnl, a myokine, adipokine and cardiokine, plays a significant role in the pathogenesis of various cardiomyopathies. Therefore, the objective of this review is to examine the role and mechanism of Metrnl in various cardiomyopathies, with the expectation of providing new insights for the treatment of these diseases.

Indexed as

CardiomyopathiesAnimalsHumansMyocardiumadipokinecardiokinecardiomyopathiesMetrnlmyokine

Identifiers

PMID39853716
PMCPMC11756984

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.