Evidence map›Paper›PMID 39854055›Full record

ReviewAnimal models and experimental medicine2025

Animal models of cisplatin-induced neuropathic pain.

Ningxin Li, Mingzhu Li, Shengbo Jin, Jun Yu, Hongzhe Wei, Wenping Wang, Siyao Ma, Yuxin Jiang, Qian Liu, Huini Yao

Abstract readReview
In one paragraph

Review in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Animal models of cisplatin-induced neuropathic pain.Animal models and experimental medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ningxin LiChina Medical University, Shenyang, China.ORCID 0009-0001-4012-787X
Mingzhu LiCancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Sheng Yang, China.ORCID 0009-0009-5682-3405
Shengbo JinLiaoning University of Traditional Chinese Medicine, Shenyang, China.
Jun YuLiaoning University of Traditional Chinese Medicine, Shenyang, China.
Hongzhe WeiChina Medical University, Shenyang, China.
Wenping WangCancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Sheng Yang, China.
Siyao MaCancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Sheng Yang, China.
Yuxin JiangLiaoning University of Traditional Chinese Medicine, Shenyang, China.
Qian LiuLiaoning University of Traditional Chinese Medicine, Shenyang, China.
Huini YaoChina Medical University, Shenyang, China.

Funding

China Health Promotion Foundation Spark Program XH-D001Liaoning Provincial Key Research and Development Program 2024JH2/102500062National Natural Science Foundation of China 82104838
6 · The paper itself

Abstract

Cisplatin chemotherapy has been used as the main treatment for different types of cancer. However, cisplatin chemotherapy-induced peripheral neuropathic pain (CIPNP) seriously affects the treatment process and quality of life of patients. In addition, it impacts the underlying mechanism and prevention and treatment strategies, indicating that drug selection and efficacy evaluation need to be further investigated. Furthermore, an animal model that is more consistent with the pathological mechanism needs to be developed. In this study, we describe and discuss the methods of developing and detecting CIPNP models in rats and mice induced by cisplatin chemotherapy. The aim was to improve the modeling rate and develop animal models that are more consistent with the developmental pattern of the disease. In addition, the study provides ideal reference animal models for clinical research and drug discovery and development.

Indexed as

Antineoplastic AgentsCisplatinDisease Models, AnimalNeuralgiaAnimalsMiceRatsAntineoplastic AgentsCisplatinanimal modelschemotherapycisplatinperipheral neuropathic pain

Identifiers

PMID39854055
PMCPMC12431596

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.