Evidence map›Paper›PMID 39856196›Full record

ArticleNature cardiovascular research2025

Implications and limitations of the CLEAR-SYNERGY trial for the use of low-dose colchicine in cardiovascular disease.

Ashish Misra, Peter J Psaltis, Amandeep Rashid Mondal, Adam J Nelson, Stefan Mark Nidorf

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cardiovascular research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashish MisraAtherosclerosis and Vascular Remodeling Group, Heart Research Institute, Sydney, New South Wales, Australia. ashish.misra@hri.org.au.ORCID http://orcid.org/0000-0002-8901-4788
Peter J PsaltisVascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Amandeep Rashid MondalAtherosclerosis and Vascular Remodeling Group, Heart Research Institute, Sydney, New South Wales, Australia.
Adam J NelsonVascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Stefan Mark NidorfHeart and Vascular Research Institute, Harry Perkins Institute of Medical Research, Perth, Western Australia, Australia.

Funding

National Heart Foundation of Australia (Heart Foundation) FLF 106656National Heart Foundation of Australia (Heart Foundation) NHF1017NSW Ministry of Health (NSW Health) DOH1024
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39856196

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.