Evidence map›Paper›PMID 39856811›Full record

ArticleJournal of diabetes investigation2025

Impact of maternal overweight/obesity and high fasting plasma glucose on adverse perinatal outcomes in early gestational diabetes mellitus.

Noriyuki Iwama, Maki Yokoyama, Hiroshi Yamashita, Kei Miyakoshi, Ichiro Yasuhi, Maki Kawasaki, Naoko Arata, Shiori Sato, Yuko Iimura, Waguri Masako and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Noriyuki IwamaCenter for Maternal and Perinatal Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan.ORCID https://orcid.org/0000-0002-6808-0911
Maki YokoyamaDepartment of Obstetrics and Gynecology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.ORCID https://orcid.org/0000-0001-7942-6677
Hiroshi YamashitaDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura-City, Nagasaki, Japan.
Kei MiyakoshiDepartment of Obstetrics and Gynecology, International Catholic Hospital, Shinjuku-ku, Tokyo, Japan.
Ichiro YasuhiDepartment of Obstetrics and Gynecology, NHO Nagasaki Medical Center, Omura-City, Nagasaki, Japan.
Maki KawasakiDepartment of Health Policy, National Center for Child Health and Development, Setagaya, Tokyo, Japan.
Naoko ArataDivision of Women's Internal Medicine, Women's Health Center, National Center for Child Health and Development, Setagaya, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2667-7653
Shiori SatoDivision of Women's Internal Medicine, Women's Health Center, National Center for Child Health and Development, Setagaya, Tokyo, Japan.ORCID https://orcid.org/0009-0005-5053-6641
Yuko IimuraDivision of Women's Internal Medicine, Women's Health Center, National Center for Child Health and Development, Setagaya, Tokyo, Japan.
Waguri MasakoDepartment.of Obstetric Medicine, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan.
Haruna KawaguchiDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan.
Naoki MasaokaDepartment of Obstetrics and Gynecology, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.
Yoshiyuki NakajimaDepartment of Obstetrics and Gynecology, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.
Yuji HiramatsuOkayama City General Medical Center, Okayama City, Okayama, Japan.
Takashi SugiyamaDepartment of Obstetrics and Gynecology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
DREAMBee Study Gestational Diabetes Mellitus Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo elucidate risk factors associated with adverse perinatal outcomes in early-gestational diabetes mellitus (GDM). MATERIALS AND

methodsA dataset of 385 early-GDM cases from a prospective cohort was analyzed. Early-GDM was diagnosed if one or more of the following criteria were met: fasting plasma glucose (PG) levels of 92-125 mg/dL, 1-h PG levels ≥180 mg/dL, and 2-h PG levels ≥153 mg/dL during a 75-g oral glucose tolerance test before 20 weeks of gestation. Multivariate analysis was used to examine associations between candidate risk factors and a composite outcome of maternal and neonatal adverse events.

resultsPre-pregnancy overweight/obesity (pre-pregnancy body mass index [BMI] ≥25.0 kg/m

conclusionsEarly-GDM, combined with pre-pregnancy overweight/obesity and/or fasting PG levels of 95-125 mg/dL, is associated with a higher risk of adverse perinatal outcomes and should be prioritized for intervention.

Indexed as

Blood GlucoseDiabetes, GestationalFastingObesityOverweightPregnancy in ObesityAdultBody Mass IndexFemaleFollow-Up StudiesGlucose Tolerance TestHumansInfant, NewbornPregnancyPregnancy OutcomePrognosisBlood GlucoseEarly gestational diabetes mellitusFasting plasma glucoseOverweight/obesity

Identifiers

PMID39856811
PMCPMC11970313

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.