Evidence map›Paper›PMID 39856887›Full record

ArticleFoods (Basel, Switzerland)2025

L-Theanine Extends the Lifespan of

Zhihang Huang, Haiming Jing, Yan Pan, Hongxia Cai, Wenjing Zhang, Jingyuan Zhu, Nan Zhang, Dan Wu, Wentao Xu, Hexiang Qiu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. International journal of molecular sciences · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zhihang HuangBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Haiming JingBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Yan PanLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.ORCID 0009-0003-3713-8329
Hongxia CaiLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.
Wenjing ZhangBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Jingyuan ZhuLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.
Nan ZhangBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Dan WuLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.
Wentao XuLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.
Hexiang QiuLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.
Huihui BaoNHC Key Laboratory of Food Safety Risk Assessment, Chinese Academy of Medical Science Research Unit, China National Center for Food Safety Risk Assessment, Beijing 100022, China.ORCID 0000-0002-5583-3187
Guojun LiBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Junyu NingBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Bo XianLaboratory of Aging Research, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610056, China.ORCID 0009-0006-1873-8435
Shan GaoBeijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.

Funding

National Key Research and Development Program of China 2023YFF1103804the Science and Technology Program of Beijing Z231100004523001
6 · The paper itself

Abstract

L-theanine, a non-protein amino acid naturally occurring in tea leaves, is recognized for its antioxidant, anti-inflammatory, and neuroprotective properties. Despite its known benefits, the mechanisms by which L-theanine influences lifespan extension remain poorly understood. This study investigated the effects of L-theanine on the lifespan of

Indexed as

advanced glycation end products (AGEs)Caenorhabditis elegansinsulin-like signalinglifespan extensionL-theanine

Identifiers

PMID39856887
PMCPMC11764849

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.