Evidence map›Paper›PMID 39857600›Full record

ReviewBiomedicines2024

Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke.

Grace Hey, Ilyas Mehkri, Yusuf Mehkri, Hasan Maqbool, Mubariz Tahirkheli, Samuel Woodford, Brandon Lucke-Wold

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Grace HeyCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-9838-7738
Ilyas MehkriCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0009-0004-9196-4143
Yusuf MehkriCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.
Hasan MaqboolCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.
Mubariz TahirkheliCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0009-0001-6773-4485
Samuel WoodfordCollege of Medicine, University of Florida, Gainesville, FL 32610, USA.
Brandon Lucke-WoldLillian S. Wells Department of Neurosurgery, College of Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA.ORCID 0000-0001-6577-4080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpredictable. Nanoparticle (NP) technology allows for deliberate, modular, and minimally invasive drug delivery. This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. Currently, notable treatments such as Perfluorooctyl-Bromide (PFOB), PLGA nanoparticles, and ischemic relief-based NPs are promising new techniques for the management of these complex pathologies.

Indexed as

nanoparticleneurotraumastrokesubarachnoid hemorrhage

Identifiers

PMID39857600
PMCPMC11760890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.