Evidence map›Paper›PMID 39857977›Full record

ArticleCancers2025

Ruthenium(II) Complex with 8-Hydroxyquinoline Exhibits Antitumor Activity in Breast Cancer Cell Lines.

Amr Khalifa, Salah A Sheweita, Asmaa Namatalla, Mohamed A Khalifa, Alessio Nencioni, Ahmed S Sultan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amr KhalifaDepartment of Internal Medicine and Medical Specialties, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.ORCID 0000-0002-2131-5496
Salah A SheweitaDepartment of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria P.O. Box 21526, Egypt.ORCID 0000-0001-8113-4403
Asmaa NamatallaDepartment of Internal Medicine and Medical Specialties, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.
Mohamed A KhalifaDepartment of Chemistry, Faculty of Science, Alexandria University, Alexandria P.O. Box 21511, Egypt.
Alessio NencioniDepartment of Internal Medicine and Medical Specialties, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.
Ahmed S SultanDepartment of Biochemistry, Faculty of Science, Alexandria University, Alexandria P.O. Box 21511, Egypt.

Funding

Associazione Italiana per la Ricerca sul Cancro (AIRC) to Alessio Nencioni 22098Breast Cancer Research Program (US Department of Defense; to Alessio Nencioni) BC161452P1Funds to the Ospedale Policlinico San Martino IRCCS to Alessio Nencioni 5 × 1000 2014
6 · The paper itself

Abstract

BACKGROUND/

objectivesBreast cancer (BC) remains one of the most prevalent and deadly cancers worldwide, with limited access to advanced treatments in developing regions. There is a critical need for novel therapies with unique mechanisms of action, especially to overcome resistance to conventional platinum-based drugs. This study investigates the anticancer potential of the ruthenium complex Bis(quinolin-8-olato)bis(triphenylphosphine)ruthenium(II) (Ru(quin)

resultsRu(quin)

conclusionsRu(quin)

Indexed as

apoptosisautophagybreast cancercell cycleruthenium complex

Identifiers

PMID39857977
PMCPMC11763687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.