Evidence map›Paper›PMID 39858391›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Evaluation of Cinnamon Essential Oil and Its Emulsion on Biofilm-Associated Components of

Tea Ganić, Ilinka Pećinar, Biljana Nikolić, Dušan Kekić, Nina Tomić, Stefana Cvetković, Stefana Vuletić, Dragana Mitić-Ćulafić

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tea GanićFaculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.
Ilinka PećinarFaculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.ORCID 0000-0002-5332-4696
Biljana NikolićFaculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.ORCID 0000-0003-1765-2454
Dušan KekićFaculty of Medicine, Institute of Microbiology and Immunology, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-0327-4838
Nina TomićGroup for Biomedical Engineering and Nanobiotechnology, Institute of Technical Science of SASA, Kneza Mihaila 35/IV, 11000 Belgrade, Serbia.ORCID 0000-0003-0086-0054
Stefana CvetkovićFaculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.ORCID 0000-0001-9214-4682
Stefana VuletićFaculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.ORCID 0000-0001-8868-474X
Dragana Mitić-ĆulafićFaculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.ORCID 0000-0002-6651-6814

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsIn order to evaluate the antibiofilm activity, crystal violet assay was performed to determine biofilm biomass. The main components of the biofilm matrix were measured as well as the motile capacity of the tested strains. Gene expression was monitored with RT-qPCR, while treated biofilms were observed with Raman spectroscopy.

resultsA particularly strong potential against pre-formed biofilm with a decreased biomass of up to 66% was found. The effect was monitored not only with regard to the whole biofilm biomass, but also on the individual components of the biofilm matrix such as exopolysaccharides, proteins, and eDNA molecules. Protein share drops in treated biofilms demonstrated the most consistency among strains and rose to 75%. The changes in strain motility and gene expressions were investigated after the treatments were carried out. Raman spectroscopy revealed the influence of the studied compounds on chemical bond types and the components present in the biofilm matrix of the tested strains.

conclusionsThe results obtained from this research are promising regarding cinnamon essential oil and its emulsion as potential antibiofilm agents, so further investigation of their activity is encouraged for their potential use in biomedical applications.

Indexed as

Acinetobacter baumanniibiofilmcinnamon essential oilemulsiongene expressionRaman spectroscopy

Identifiers

PMID39858391
PMCPMC11761628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.